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Merck

P1584

Sigma-Aldrich

肽基精氨酸脱亚胺酶 来源于兔骨骼肌

buffered aqueous glycerol solution, ≥200 units/mg protein (Bradford)

别名:

蛋白质精氨酸亚氨基水解酶

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About This Item

CAS号:
MDL號碼:
分類程式碼代碼:
12352204
NACRES:
NA.54

形狀

buffered aqueous glycerol solution

品質等級

比活性

≥200 units/mg protein (Bradford)

相關疾病

arthritis (rheumatoid )

運輸包裝

dry ice

儲存溫度

−70°C

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一般說明

肽基精氨酸脱亚胺酶是将精氨酸转化为瓜氨酸的酶。

應用

肽基精氨酸脱亚胺酶已被用于一项评估了有前途的新型生物标志物,用于类风湿性关节炎的早期诊断的研究。 也有研究用于探讨牙周炎和类风湿关节炎的自身致病相关性。

生化/生理作用

在体外,钙是肽酰精氨酸脱亚胺酶活性所必需的

單位定義

一个单位将在55°C,pH 7.2下每小时从BAEE产生 1μN-α 摩尔苯甲酰瓜氨酸乙酯。

外觀

溶液溶于 20 mM Tris-HCl,pH 7.4,含 10 mM 2-巯基乙醇、1 mM EDTA 和 10% 甘油

象形圖

Health hazard

訊號詞

Danger

危險聲明

防範說明

危險分類

Resp. Sens. 1

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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An enzyme which catalyzes the coversion of arginyl residues to citrullyl residues in protein was obtained from the extract of the epidermis of newborn rats. The enzyme required Ca2+ for its activity. The enzyme activity was enhanced in the presence
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Journal of molecular biology, 367(4), 1118-1129 (2007-02-17)
Peptidylarginine deiminase (PAD) enzymes catalyze the conversion of arginine residues in proteins to citrulline residues. Citrulline is a non-standard amino acid that is not incorporated in proteins during translation, but can be generated post-translationally by the PAD enzymes. Although the

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