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Merck

O6881

Sigma-Aldrich

奥昔嘌醇

≥98% (HPLC)

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About This Item

经验公式(希尔记法):
C5H4N4O2
CAS号:
分子量:
152.11
EC號碼:
MDL號碼:
分類程式碼代碼:
41106305
PubChem物質ID:
NACRES:
NA.51

品質等級

化驗

≥98% (HPLC)

形狀

powder

溶解度

1 M NaOH: 49.00-51.00 mg/mL, clear to slightly hazy, colorless to yellow (heated NaOH)

SMILES 字串

O=C1NC(=O)c2cn[nH]c2N1

InChI

1S/C5H4N4O2/c10-4-2-1-6-9-3(2)7-5(11)8-4/h1H,(H3,6,7,8,9,10,11)

InChI 密鑰

HXNFUBHNUDHIGC-UHFFFAOYSA-N

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應用

氧嘌呤醇已被用作黄嘌呤氧化酶抑制剂,以评估其对肝癌细胞增殖的影响。它也已被用作黄嘌呤抑制剂,以阐明其在诱导hpv16晚期基因表达中的作用。
氧嘌呤醇是一种别嘌呤醇代谢产物,被用作抑制剂来研究黄嘌呤氧化酶的特异性和动力学。氧嘌呤醇还通过抑制黄嘌呤氧化酶而用作抗炎药。

生化/生理作用

氧嘌呤醇具有刺激成骨细胞分化和增强骨形成的能力。用于治疗痛风和高尿酸血症。氧嘌呤醇被认为是一种强抗氧化剂。它能阻止成骨细胞黄嘌呤氧化酶(XO)的作用。
一种别嘌醇的代谢产物。

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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