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Merck

N3279

Sigma-Aldrich

单克隆抗 神经生长因子-β 小鼠抗

clone 25623, purified immunoglobulin, lyophilized powder

别名:

抗-NGF-β

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About This Item

MDL號碼:
分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

mouse

品質等級

共軛

unconjugated

抗體表格

purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

25623, monoclonal

形狀

lyophilized powder

物種活性

human, rat, mouse

技術

capture ELISA: 2-8 μg/mL (detection antibody at 0.1-0.4 μg/ml)
neutralization: 0.1-0.4 μg/mL

雜質

endotoxin, tested

同型

IgG1

UniProt登錄號

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... NGF(4803)
mouse ... Ngf(18049)

免疫原

重组人NGF-β。

生化/生理作用

神经生长因子(NGF)是神经系统发育和维持所必需的生长因子。NGF由三个非共价连接的α、β和γ亚基组成。β亚基负责NGF的生物学功能。神经生长因子(NGF)与NGF受体(NGFR)或Trk受体结合,并且可以独立地通过每个受体引发生物学反应。在胚胎和出生后早期发育以及周围神经元的维持过程中,NGF在神经元和神经嵴衍生细胞的存活和分化中很重要。NGF也与炎症和过敏反应有关。

外觀

从含碳水化合物的磷酸盐缓冲盐水中(经0.2 μm过滤)冻干。

準備報告

用蛋白质G纯化。

免責聲明

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

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儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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