M8194

Anti-MAFF (C-Terminal) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

• 别名: Anti-v-maf Avian Musculoaponeurotic Fibrosarcoma Oncogene Family, ProteinF
• MDL號碼: MFCD08705477
• 分類程式碼代碼: 12352203
• NACRES: NA.41
• 共軛: unconjugated
• application: ARR; IP; WB
• 無性繁殖: polyclonal
• 物種活性: human
• citations: 9
• 技術: immunoprecipitation (IP): 2-4 μL using A431 cell line; microarray: suitable; western blot: 1:2,000-1:4,000 using whole extracts of the A431 cell line

属性

• 生物源: rabbit
• 品質等級: 200
• 共軛: unconjugated
• 抗體表格: IgG fraction of antiserum
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 形狀: buffered aqueous solution
• 分子量: antigen 18 kDa
• 物種活性: human
• 技術: immunoprecipitation (IP): 2-4 μL using A431 cell line; microarray: suitable; western blot: 1:2,000-1:4,000 using whole extracts of the A431 cell line
• UniProt登錄號: Q9ULX9
• 運輸包裝: dry ice
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... MAFF(23764)

说明

一般說明

The MAFF gene is located on the human chromosome at 22q13.1. The encoded protein is a small MAF protein and is expressed in the nucleus.

v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F (MAFF) is a transcription factor which does not have a transactivation domain but possesses a leucine-zipper.

特異性

Anti-MAFF (C-terminal) specifically recognizes MAFF.

免疫原

synthetic peptide corresponding to amino acids 147-163 of human MAFF (isoform a). The immunizing peptide does not cross-react with other members of the family.

應用

Anti-MAFF (c-terminal) antibody produced in rabbit has been used in:

• western blotting
• chromatin immunoprecipitation (chip)
• co-immunoprecipitation
• immunoprecipitation

生化／生理作用

The small MAF proteins are associated with many physiological processes including development, differentiation, hematopoiesis and stress response. Interestingly, these proteins regulate the stress response via different mechanisms. The MAFF gene is down-regulated in diabetes mellitus 1 patient. This gene is underexpressed in acute lymphoblastic lymphoma (ALL) patients.

v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F (MAFF) has been shown to interact with other transcription factors and it associates with certain regulatory sequences in the gene encoding the oxytocin receptor.

外觀

Solution in 0.01 M phosphate buffered saline, pH 7.4, and 15 mM sodium azide.

儲存和穩定性

For continuous use, store at 2-8 °C for up to one month. For extended storage, freeze in working aliquots. Repeated freezing and thawing, or storage in “frost-free” freezers, is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilutions should be discarded if not used within 12 hours.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全信息

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)