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Merck

M7898

Sigma-Aldrich

单克隆抗 Thy 1.1 小鼠抗

clone TN-26, purified immunoglobulin, buffered aqueous solution

别名:

Anti-CD90, Anti-CDw90

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About This Item

MDL號碼:
分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

mouse

共軛

unconjugated

抗體表格

purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

TN-26, monoclonal

形狀

buffered aqueous solution

物種活性

mouse

技術

complement-mediated cytotoxicity assay: suitable
indirect immunofluorescence: suitable

同型

IgM

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

mouse ... Thy1(21838)

一般說明

单克隆抗 Thy 1.1(小鼠 IgM 同种型)来源于小鼠骨髓瘤细胞与免疫小鼠脾细胞融合产生的杂交瘤。
胸腺细胞抗原 1 (Thy 1.1) 是一种糖基磷脂酰锚定蛋白。它属于免疫球蛋白超家族。Thy 1.1 在干细胞、T 细胞和神经元中表达。

特異性

识别Thy 1.1轴承细胞,与Thy 1.2轴承细胞的交叉反应小于5%。根据对AKR / J胸腺细胞的体外细胞毒性测定,滴度为1:20,000

免疫原

AKR/J (Thy 1.1) 小鼠的胸腺细胞。

應用

小鼠源抗Thy 1.1单克隆抗体可用于免疫淘选和免疫荧光。

生化/生理作用

研究表明,缺乏蛋白质胸腺细胞抗原 1 (Thy 1.1) 的小鼠成纤维细胞数量增加。这种成分可抑制真皮成纤维细胞的增殖并增强其凋亡,从而调节细胞生长。此过程通过调节β3整合素的作用实现。

外觀

0.1 M磷酸盐缓冲液(pH 7.4,含有15 mM叠氮化钠)溶液

免責聲明

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

nwg

閃點(°F)

Not applicable

閃點(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Journal of neuroscience research, 31(4), 622-634 (1992-04-01)
The neu gene, which encodes a putative tyrosine kinase growth factor receptor termed p185neu, was originally identified as a dominant transforming gene in neurogliomas and schwannomas induced by transplacental treatment of rat embryos with ethylnitrosourea. The present studies were undertaken
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American journal of physiology. Cell physiology, 309(9), C616-C626 (2015-09-04)
Idiopathic pulmonary fibrosis is a progressive lung disease that increases in incidence with age. We identified a profibrotic lung phenotype in aging mice characterized by an increase in the number of fibroblasts lacking the expression of thymocyte differentiation antigen 1
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