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Merck

M6882

Sigma-Aldrich

甲基α-D-吡喃甘露糖苷

≥99.0% (HPLC)

别名:

α-甲基D-甘露糖苷

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About This Item

经验公式(希尔记法):
C7H14O6
CAS号:
分子量:
194.18
Beilstein:
81566
EC號碼:
MDL號碼:
分類程式碼代碼:
12352201
PubChem物質ID:
NACRES:
NA.25

化驗

≥99.0% (HPLC)

形狀

powder

光學活性

[α]20/D 77.0 to 82.0°, c = 1-10% (w/v) in water

技術

HPLC: suitable

顏色

white to off-white

mp

193-196 °C (lit.)

溶解度

water: 100 mg/mL, clear, colorless

儲存溫度

15-25°C

SMILES 字串

CO[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]1O

InChI

1S/C7H14O6/c1-12-7-6(11)5(10)4(9)3(2-8)13-7/h3-11H,2H2,1H3/t3-,4-,5+,6+,7+/m1/s1

InChI 密鑰

HOVAGTYPODGVJG-VEIUFWFVSA-N

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一般說明

甲基 α-D-吡喃甘露糖苷是大肠杆菌结合甘露糖的竞争抑制剂。

應用

已经使用甲基 α-D-吡喃甘露糖苷合成一系列三- 和四羟基化的七元亚氨基糖,该研究致力于具有 D-甘露糖构型的稳定的诺罗霉素类似物。 它也被用于研究普拉定霉素 A 的主要甘露糖结合位点。

其他說明

为了全面了解我们针对客户研究提供的各种单糖产品,建议您访问我们的碳水化合物分类页面。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

404.1 °F

閃點(°C)

206.74 °C

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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M Aronson et al.
The Journal of infectious diseases, 139(3), 329-332 (1979-03-01)
Methyl alpha-D-mannopyranoside (alpha MM), a competitor inhibitor of the binding of mannose by Escherichia coli, was tested for its ability to prevent infection of the urinary tract of mice with infective strains of the organisms. Injection of the bacteria in
Yu Nakagawa et al.
Journal of the American Chemical Society, 133(43), 17485-17493 (2011-09-29)
Pradimicin A (PRM-A) is an actinomycete-derived antibiotic with the lectin-like property of being able to recognize D-mannopyranoside (Man) in the presence of Ca(2+) ion. PRM-A and its derivatives have been attracting a great deal of attention as the only family
Julia Deschamp et al.
Bioorganic & medicinal chemistry, 20(2), 641-649 (2010-10-26)
Noeuromycin is a highly potent albeit unstable glycosidase inhibitor due to its hemiaminal function. While stable D-gluco-like analogs have been reported, no data are available for D-manno-like structures. A series of tri- and tetrahydroxylated seven-membered iminosugars displaying either a D-manno-or
Oliver Schwardt et al.
Bioorganic & medicinal chemistry, 19(21), 6454-6473 (2011-10-04)
Urinary tract infection (UTI) caused by uropathogenic Escherichia coli (UPEC) is one of the most prevalent infectious diseases. Particularly affected are women, who have a 40-50% risk to experience at least one symptomatic UTI episode at some time during their
Karen T Welch et al.
Bioorganic & medicinal chemistry letters, 18(24), 6573-6575 (2008-11-08)
A virtual screening approach was used to identify new glycomimetics. The National Cancer Institute Diversity Set was docked into the carbohydrate binding site of the lectin concanavalin A (ConA). The resulting poses were analyzed and 19 molecules were tested for

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