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About This Item
经验公式（希尔记法）:
C7H15NO4
CAS号:
分子量:
177.20
Beilstein:
1524564
MDL號碼:
分類程式碼代碼:
51102829
PubChem物質ID:
NACRES:
NA.32
推荐产品
生物源
synthetic (organic)
品質等級
化驗
≥98%
形狀
powder
溶解度
methanol: 10 mg/mL, clear, colorless
抗生素活性譜
viruses
作用方式
enzyme | inhibits
儲存溫度
−20°C
SMILES 字串
CN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO
InChI
1S/C7H15NO4/c1-8-2-5(10)7(12)6(11)4(8)3-9/h4-7,9-12H,2-3H2,1H3/t4-,5+,6-,7-/m1/s1
InChI 密鑰
AAKDPDFZMNYDLR-XZBKPIIZSA-N
基因資訊
mouse ... Gaa(14387) , Glb1(12091) , Treh(58866)
rat ... Man2a1(25478) , Si(497756)
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一般說明
Chemical structure: glucosamine
生化／生理作用
Interferes with metabolism of N-linked glycoproteins by inhibition of glucosidase.
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
Diego A Caraballo et al.
G3 (Bethesda, Md.), 10(2), 755-768 (2019-12-05)
UDP- glucose: glycoprotein glucosyltransferase (UGGT) is a protein that operates as the gatekeeper for the endoplasmic reticulum (ER) quality control mechanism of glycoprotein folding. It is known that vertebrates and Caenorhabditis genomes harbor two uggt gene copies that exhibit differences
K Mori et al.
Biochimica et biophysica acta, 1226(3), 300-306 (1994-07-18)
We studied the effect of the glucosidase I inhibitor, N-methyl-1-deoxynojirimycin (MdN) and the mannosidase inhibitor, 1-deoxymannojirimycin (dMM) on the biosynthesis and secretion of alpha 2-plasmin inhibitor (alpha 2-PI) and antithrombin III (ATIII) in cultures of human hepatoma (Hep-G2) cells. Incubation
M Arai et al.
Circulation, 97(13), 1290-1297 (1998-05-07)
N-methyl-1-deoxynojirimycin (MOR-14), an alpha-glucosidase inhibitor, reduces the glycogenolytic rate by inhibiting the alpha-1,6-glucosidase of glycogen-debranching enzyme in the liver, in addition to possessing an antihyperglycemic action by blocking alpha-1,4-glucosidase in the intestine. Because the reduction of the glycogenolytic rate may
M Kengaku et al.
Brain research. Developmental brain research, 60(2), 133-136 (1991-06-21)
The effect of myogenic differentiation on the expression of choline acetyltransferase (ChAT) activity in co-cultured spinal cord neurons was studied. ChAT activity in spinal cord cells dissociated from 14-day mouse embryos was markedly increased when co-cultured with skeletal myotubes from
J C Ridruejo et al.
Biochimica et biophysica acta, 993(2-3), 179-185 (1989-12-08)
Castanospermine, 1-deoxynojirimycin, and N-methyl-1-deoxynojirimycin, three well-characterized inhibitors of the glucosidases involved in the processing of N-linked oligosaccharides, did not affect the biosynthesis or the secretion of exoglucanases (EC 3.2.1.58) from Saccharomyces cerevisiae and Candida albicans but inhibited the activity itself.
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