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product name
L-亮氨酸, reagent grade, ≥98% (HPLC)
等級
reagent grade
品質等級
化驗
≥98% (HPLC)
形狀
powder
技術
ligand binding assay: suitable
雜質
isoleucine and methionine, essentially free
顏色
white to off-white
mp
>300 °C (lit.)
應用
peptide synthesis
SMILES 字串
CC(C)C[C@H](N)C(O)=O
InChI
1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m0/s1
InChI 密鑰
ROHFNLRQFUQHCH-YFKPBYRVSA-N
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相关类别
應用
L-亮氨酸已被用作雷帕霉素(mTOR)机制靶标的激动剂,以确定AMPK/mTOR途径是否参与小檗碱介导的J774A.1细胞自噬。它也被用于转化后细胞的选择。
生化/生理作用
亮氨酸是一种非生糖必需氨基酸。它是一种支链氨基酸,是蛋白质的结构组分。亮氨酸对胰岛素的释放可产生积极影响,从而消除血液中的毒性糖。亮氨酸的降解会导致酮体的形成。
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 1
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
其他客户在看
The Leucine Factor Diet: The Scientifically-Proven Approach to Combat Sugar, Burn Fat and Build Muscle (2015)
Berberine alleviates ox-LDL induced inflammatory factors by up-regulation of autophagy via AMPK/mTOR signaling pathway
Journal of Translational Medicine (2015)
Cells, 9(12) (2020-12-06)
In this study we surveyed a rat skeletal muscle RNA-Seq for genes that are induced by hindlimb immobilization and, in turn, become attenuated by leucine supplementation. This approach, in search of leucine-atrophy protection mediating genes, identified histone deacetylase 4 (HDAC4)
Markerless Gene Editing in the Hyperthermophilic Archaeon Thermococcus kodakarensis
Bio-protocol (2017)
Ketogenic Diet and Metabolic Therapies: Expanded Roles in Health and Disease (2016)
Chromatograms
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