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Merck

K2010

Sigma-Aldrich

α-酮戊二酸钠 钠盐

BioUltra

别名:

2-氧代戊二酸 单钠盐, 2-氧化戊二酸 单钠盐, 2-酮戊二酸钠 一元

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About This Item

线性分子式:
HOOCCH2CH2COCOONa
CAS号:
分子量:
168.08
Beilstein:
4597521
EC號碼:
MDL號碼:
分類程式碼代碼:
12352204
PubChem物質ID:
NACRES:
NA.32

產品線

BioUltra

品質等級

化驗

≥98% (perchloric acid titration)

形狀

powder

雜質

≤0.0005% Phosphorus (P)
≤0.1% Insoluble matter

溶解度

H2O: 0.5 M, clear, colorless

負離子痕跡

chloride (Cl-): ≤0.05%
sulfate (SO42-): ≤0.05%

正離子痕跡

Al: ≤0.0005%
Ca: ≤0.001%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Mg: ≤0.0005%
NH4+: ≤0.05%
Pb: ≤0.001%
Zn: ≤0.0005%

儲存溫度

2-8°C

SMILES 字串

[Na+].OC(=O)CCC(=O)C([O-])=O

InChI

1S/C5H6O5.Na/c6-3(5(9)10)1-2-4(7)8;/h1-2H2,(H,7,8)(H,9,10);/q;+1/p-1

InChI 密鑰

MOTOGHHLNTXPTI-UHFFFAOYSA-M

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應用

α-酮戊二酸钠盐已用于人犬尿氨酸氨基转移酶II(KAT-II)的抑菌谱测定。

生化/生理作用

α-酮戊二酸是L-谷氨酸的前体。
α-酮戊二酸是TCA循环中的关键中间体。它还可与细胞内释放的氮结合,从而在防止氮超载方面发挥重要作用。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Amino Acids in Therapy: A Guide to the Therapeutic Application of Protein Constituents, 34-34 (1985)
Structure-based design of irreversible human KAT II inhibitors: Discovery of new potency-enhancing interactions
Tuttle JB, et al.
ACS Medicinal Chemistry Letters, 4(1), 37-40 (2012)
Michael E Jung et al.
The Journal of organic chemistry, 77(23), 11002-11005 (2012-11-21)
Oxidative cleavage of cycloalkene-1-carboxylates, made from the corresponding carboxylic acids, and subsequent oxidation of the resulting ketoaldehyde afforded the important 1-monoesters of 2-ketoalkanedioic acids. Thus ozonolysis of octyl cyclobutene-1-carboxylate followed by sodium chlorite oxidation afforded the 1-monooctyl 2-ketoglutarate. This is
Vivian R Moure et al.
Journal of bacteriology, 195(2), 279-286 (2012-11-13)
Fe protein (dinitrogenase reductase) activity is reversibly inactivated by dinitrogenase reductase ADP-ribosyltransferase (DraT) in response to an increase in the ammonium concentration or a decrease in cellular energy in Azospirillum brasilense, Rhodospirillum rubrum, and Rhodobacter capsulatus. The ADP-ribosyl is removed
Kenji Manabe et al.
Microbial cell factories, 12, 18-18 (2013-02-20)
The Bacillus subtilis genome-reduced strain MGB874 exhibits enhanced production of exogenous extracellular enzymes under batch fermentation conditions. We predicted that deletion of the gene for RocG, a bi-functional protein that acts as a glutamate dehydrogenase and an indirect repressor of

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