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Merck

I0909

Sigma-Aldrich

6-Iodonordihydrocapsaicin

≥98% (HPLC), solid

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About This Item

经验公式(希尔记法):
C17H26INO3
分子量:
419.30
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77

品質等級

化驗

≥98% (HPLC)

形狀

solid

儲存條件

protect from light

顏色

white

溶解度

DMSO: ~44 mg/mL
H2O: insoluble

儲存溫度

2-8°C

SMILES 字串

CCCCCCCCC(=O)NCc1cc(OC)c(O)cc1I

InChI

1S/C17H26INO3/c1-3-4-5-6-7-8-9-17(21)19-12-13-10-16(22-2)15(20)11-14(13)18/h10-11,20H,3-9,12H2,1-2H3,(H,19,21)

InChI 密鑰

AAORACFZMYMFCG-UHFFFAOYSA-N

基因資訊

human ... TRPV1(7442)

生化/生理作用

TRPV1 (V1) vanilloid receptor antagonist.

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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Giovanni Appendino et al.
British journal of pharmacology, 139(8), 1417-1424 (2003-08-19)
1. The C-5 halogenation of the vanillyl moiety of resiniferatoxin, an ultrapotent agonist of vanilloid TRPV1 receptors, results in a potent antagonist for these receptors. Here, we have synthesized a series of halogenated derivatives of 'synthetic capsaicin' (nonanoyl vanillamide=nordihydrocapsaicin) differing
Yuriko Oi-Kano et al.
The Journal of nutritional biochemistry, 40, 209-218 (2016-12-13)
Oleuropein is the pungent principle of raw olives. Oleuropein aglycone (OA) is a major phenolic compound in extra virgin olive oil and the absorbed form of oleuropein. We aimed to determine the mechanism underlying the nutritional effects of oleuropein and
Daniela L Uliana et al.
Journal of psychopharmacology (Oxford, England), 34(9), 1043-1055 (2020-07-09)
Blockade of cannabinoid CB1 or vanilloid TRPV1 receptors in the ventromedial prefrontal cortex of rats respectively increases or decreases the conditioned emotional response during re-exposure to a context previously paired with footshocks. Although these mechanisms are unknown, they may involve
Manoela V Fogaça et al.
Pharmacology, biochemistry, and behavior, 129, 7-13 (2014-12-03)
Hemopressin (PVNFKFLSH; HP) is an orally active peptide derived from rat hemoglobin α-chain that could act as an inverse agonist at cannabinoid type 1 receptors (CB1). Here, we aim to investigate possible behavioral effects of HP in male Wistar rats
Azucena Perez-Burgos et al.
The Journal of physiology, 593(17), 3943-3957 (2015-06-19)
Certain probiotic bacteria have been shown to reduce distension-dependent gut pain, but the mechanisms involved remain obscure. Live luminal Lactobacillus reuteri (DSM 17938) and its conditioned medium dose dependently reduced jejunal spinal nerve firing evoked by distension or capsaicin, and

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