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Merck

I0380

Sigma-Aldrich

D-allo-Isoleucine

别名:

(2R,3S)-2-Amino-3-methylpentanoic acid

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About This Item

线性分子式:
CH3CH2CH(CH3)CH(NH2)CO2H
CAS号:
分子量:
131.17
Beilstein:
1721794
EC號碼:
MDL號碼:
分類程式碼代碼:
12352209
PubChem物質ID:
NACRES:
NA.26

化驗

≥98% (HPLC)

品質等級

形狀

powder

光學活性

[α]20/D −38° in 6 M HCl

顏色

white to off-white

mp

291 °C (dec.) (lit.)

應用

peptide synthesis

SMILES 字串

CC[C@H](C)[C@@H](N)C(O)=O

InChI

1S/C6H13NO2/c1-3-4(2)5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t4-,5+/m0/s1

InChI 密鑰

AGPKZVBTJJNPAG-CRCLSJGQSA-N

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應用

D-allo-Isoleucine is used in the synthesis of a conjugate of epi-jasmonic acid and various antimicrobial peptides.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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N Ogawa et al.
Amino acids, 42(5), 1955-1966 (2011-05-13)
The TES ether of the C6-hydroxy derivative of naturally occurring epi-jasmonic acid (epi-JA) was designed as epimerization-free equivalent of epi-JA. The TES ether was synthesized from (1R,4S)-4-hydroxycyclopent-2-enyl acetate in 13 steps. The acid part of the ether was activated with
Koichi Narita et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 15(42), 11174-11186 (2009-09-18)
The bicyclic depsipeptide histone deacetylase (HDAC) inhibitors spiruchostatins A and B, 5''-epi-spiruchostatin B and FK228 were efficiently synthesized in a convergent and unified manner. The synthetic method involved the following crucial steps: i) a Julia-Kocienski olefination of a 1,3-propanediol-derived sulfone
G Kreil
Ciba Foundation symposium, 186, 77-85 (1994-01-01)
Over the past three decades, numerous peptides have been isolated from amphibian skin secretions. Many of these peptides were shown to be homologous to hormones and neurotransmitters of mammals. In recent years it has been shown that these secretions also

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