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應用
肝素黄杆菌肝素酶III已用于裂解特定GAG。已用于研究其对与抗aFGF(酸性成纤维细胞生长因子)抗体反应的蛋白质的电泳迁移率的影响。
生化/生理作用
肝素酶III可防止体内新血管的形成。它在HNY-I和HNY、6X-G2连接处特异性降解硫酸肝素。与其他肝素酶不同,肝素酶III不含氨基酸半胱氨酸。它含有13个组氨酸残基,这是其催化作用的原因。该酶对肝素或低分子量肝素没有活性。
肝素降解裂解酶,识别硫酸肝素蛋白聚糖为其主要底物。
單位定義
在25 °C、pH 7.5条件下,一个单位每小时可形成0.1 μM不饱和糖醛酸。一个国际单位(I.U.)相当于大约600个Sigma单位。包装规格基于Sigma单位。
其他說明
訊號詞
Danger
危險聲明
危險分類
Resp. Sens. 1
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
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商品
A key resource feature at our Enzyme Explorer section of biochemicals is "Enzymes for Carbohydrate Analysis and Digestion." Offering kits, reagents, analysis, lists of enzymes related to PTM and carbohydrate metabolism.
A key resource feature at our Enzyme Explorer section of biochemicals is "Enzymes for Carbohydrate Analysis and Digestion." Offering kits, reagents, analysis, lists of enzymes related to PTM and carbohydrate metabolism.
Glycosaminoglycans are large linear polysaccharides constructed of repeating disaccharide units.
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