推荐产品
化驗
≥97%
形狀
powder
溶解度
H2O: soluble
alcohol: soluble
chloroform: soluble
SMILES 字串
Cl[H].Cl[H].OCCOCCN1CCN(CC1)C(c2ccccc2)c3ccc(Cl)cc3
InChI
1S/C21H27ClN2O2.2ClH/c22-20-8-6-19(7-9-20)21(18-4-2-1-3-5-18)24-12-10-23(11-13-24)14-16-26-17-15-25;;/h1-9,21,25H,10-17H2;2*1H
InChI 密鑰
ANOMHKZSQFYSBR-UHFFFAOYSA-N
基因資訊
human ... HRH1(3269)
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一般說明
Hydroxyzine dihydrochloride (HDH) is the first-generation antihistamine, that belongs to the piperazine class, an H1 receptor antagonist.
應用
Hydroxyzine dihydrochloride has been used in the study of comparative anxiolytic activity of various drugs in experimental models of rats.
生化／生理作用
Hydroxyzine dihydrochloride (HDH) is used to regulate anxiety. It is also used to treat bronchial asthma and to relax patients before surgery.
訊號詞
Warning
危險聲明
危險分類
Acute Tox. 4 Oral - Repr. 2 - STOT SE 3
標靶器官
Central nervous system
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
其他客户在看
COMPARATIVE ANXIOLYTIC ACTIVITY OF VARIOUS DRUGS IN EXPERIMENTAL MODELS OF RATS
Vitthal K R, et al.
International Journal of Current Research and Review, 4(24), 77-77 (2012)
Acid-base titrimetric assay of hydroxyzine dihydrochloride in pharmaceutical samples
Rajendraprasad N, et al.
Chemical Industry Times / Hua Gong Shi Kan, 16(2), 127-132 (2010)
N Javaud et al.
Annales francaises d'anesthesie et de reanimation, 30(11), 848-850 (2011-10-08)
We are reporting the case of a bradykinin-mediated angioedema, secondary to the angiotensin converting enzyme inhibitors, which delayed treatment could have unfavorably influence the vital prognostic of the patient. Initially, the patient had an isolated edema of the superior lip.
Kaori Kimura-Kuroiwa et al.
Journal of anesthesia, 26(3), 422-428 (2012-02-22)
Investigation into the characteristics of anesthetic interactions may provide clues to anesthesia mechanisms. Dexmedetomidine, an α(2)-adrenergic receptor agonist, has become a popular sedative in intensive care, and hydroxyzine, a histamine receptor antagonist, is well known as a tranquilizing premedication for
Donatella Marazziti et al.
Current topics in medicinal chemistry, 12(4), 238-253 (2011-12-30)
Anxiety disorders represent the most prevalent psychiatric disorders. In addition, a considerable burden is associated with them, not only for individual sufferers, but also for the health care system. However, many patients who might benefit from treatment are not diagnosed
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