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product name
DL-β-羟基丁酸 钠盐, ~98%
化驗
~98%
品質等級
形狀
powder
溶解度
water: 1 g/10 mL, clear, colorless
儲存溫度
2-8°C
SMILES 字串
[Na].CC(O)CC(O)=O
InChI
1S/C4H8O3.Na/c1-3(5)2-4(6)7;/h3,5H,2H2,1H3,(H,6,7);/q;+1/p-1
InChI 密鑰
NBPUSGBJDWCHKC-UHFFFAOYSA-M
應用
DL-β-羟丁酸钠盐已用于：
- 作为标准物定量测定丹麦泽西奶牛血浆和乳汁 β-羟基丁酸
- 研究其在癫痫诱导大鼠中的抗惊厥作用
- 诱导荷斯坦奶牛高酮血症
生化／生理作用
β-羟基丁酸是存在于肝细胞瘤胃上皮中的酮体。其与乙酰乙酸酯的相互转化可影响酸碱平衡，并与荧光测定的（烟酰胺腺嘌呤二核苷酸）NAD +偶联产生NADH。高血浆水平的 β-羟基丁酸与糖尿病酮症酸中毒有关。它以单羧酸的形式穿过血脑屏障。β-羟基丁酸可能在帕金森病模型中对多巴胺能神经变性发挥保护作用。β-羟基丁酸是 G 蛋白偶联受体 (GPR109A) 的配体，有利于抑制奶牛垂体前叶细胞 (DCAPCs) 中生长激素 (GH) 和催乳素 (PRL) 基因的分泌、转录和翻译。
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
其他客户在看
Influence of DL-beta-hydroxybutyric acid on cell proliferation and calcium influx
Cheng S, et al.
Biomacromolecules, 6(2), 593-597 (2005)
Fluorometric determination of beta-hydroxybutyrate in milk and blood plasma
Larsen T and Nielsen NI
Journal of Dairy Science, 88(6), 2004-2009 (2005)
Emily R Cope et al.
Physiological genomics, 50(6), 468-477 (2018-04-07)
To identify molecular pathways that couple metabolic imbalances and reproduction, we randomly assigned 10 castrated male sheep to be centrally injected into the lateral ventricle through intracerebroventricular cannulas with 1 ml of β-hydroxybutyric acid sodium salt solution (BHB; 12,800 µmol/l)
Jianping Si et al.
Experimental and therapeutic medicine, 14(1), 765-770 (2017-07-05)
The present study aimed to investigate the anticonvulsant effects of β-hydroxybutyrate (BHB) in a kainic acid (KA)-induced rat seizure model. The concentrations of BHB and glucose were detected in the blood prior to exogenous BHB administration. Three different doses of
M Lehmann et al.
Journal of dairy science, 96(2), 889-896 (2012-12-12)
During a mammary immune response, the integrity of the blood-milk barrier is negatively affected and becomes leaky. The aim of the present study was to demonstrate the blood origin, and to investigate changes in the concentration, of various constituents including
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