GS71

GST K1-1, Recombinant Human

• 别名: GST, GST 13-13, GST13, GST13-13, GSTK1-1, glutathione S-transferase kappa, hGSTK1
• 分類程式碼代碼: 12352200
• NACRES: NA.26

属性

• 生物源: human
• 品質等級: 100
• 重組細胞: expressed in E. coli
• 化驗: >95% (SDS-PAGE)
• 形狀: frozen liquid
• 比活性: 12.22 units/mg protein
• 分子量: 26 kDa
• 濃度: 3.17 mg/mL
• 儲存溫度: −70°C
• 基因資訊: human ... GSTK1(373156)

说明

一般說明

using spectrophotometric determination of 1-chloro-2,4-dinitrobenzene (CDNB) conjugation with reduced glutathione (1 mM) in 100 mM NaPO4 (pH 6.5) at room temperature.

生化／生理作用

Glutathione S-transferase kappa 1 (GSTK1) is an enzyme that in humans is encoded by the GSTK1 gene. Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. The GSTs are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases.

This gene encodes a member of the kappa class of the glutathione transferase superfamily of enzymes that function in cellular detoxification. The encoded protein is localized to the peroxisome and catalyzes the conjugation of glutathione to a wide range of hydrophobic substates facilitating the removal of these compounds from cells. Alternative splicing results in multiple transcript variants.

儲存和穩定性

The enzyme should be used by the end-user customer within 1 year of receipt.

安全信息

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable