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形狀
solid
特點
wetted part: no
包裝
pack of 100 g
製造商／商標名
Cytiva RPN6301
顏色
White
pH值範圍
5-7
溶解度
cold water: soluble (Soluble in cold water and hot water)
diethyl ether: soluble (Partially soluble in diethyl ether)
methanol: soluble (Easily soluble in methanol)
一般說明
Thiourea is a chaotrope used together with urea in the IPG strip rehydration to solubilize and denature proteins, and improve the solubility of membrane proteins.
應用
Thiourea has been used as a component of lysis buffer for solubilization of the proteins from tissue samples and T-leukemia cells. It has also been used as a component of sample buffer for placental tissue, leaf proteome, and 2D electrophoresis.
生化／生理作用
Thiourea is an organic compound and its derivatives have antibacterial, antiviral, antifungal and insecticidal property. It is actively used in the drug development against human immunodeficiency virus (HIV) and hepatitis C infection. Thiourea inhibits cyclooxygenase enzyme and effectively reduces prostaglandin E2 (PGE2) and thromboxane (TXB2) production and is antithrombotic in human platelets. It is cytotoxic to vaginal epithelial cells and may function as potent spermicidal agent. Thiourea based derivatives of anticancer drug sorafenib, eliclits antiproliferative activity in human colon cancer cell line, HCT116 cells.
儲存和穩定性
Please be aware this product may be shipped 90 days before the expiration date. For more information on the batch specific expiration date, please contact technical service.
分析報告
To view the Certificate of Analysis for this product, please visit www.cytiva.com.
訊號詞
Warning
儲存類別代碼
13 - Non Combustible Solids
Novel thiourea compounds as dual-function microbicides
D?Cruz, OJ, et al.
Biology of Reproduction, 63(1), 196-205 (2000)
Synthesis and antiplatelet activity of antithrombotic thiourea compounds: biological and structure-activity relationship studies
Lourencco A, et al.
Molecules (Basel), 20(4), 7174-7200 (2015)
Synthesis, Characterization, Biological Activity and Use of Thiourea Derivative (PhTTU) Studies of dinitrate-1-phenyl-3-(thiazol-2-yl)-2-thioureato Cd (II) ion Complex
Alfallous KA and Aburzeza MM
International Journal of Scientific Research, 4(6) (2015)
Capabilities using 2-D DIGE in proteomics research
Tissue proteomics, 1-18 (2008)
Spontaneous Unexplained Preterm Labor with Intact Membrane: Finding Protein Biomarkers through Placenta Proteome
Electrophoresis-Life Sciences Practical Applications (2018)
商品
This page describes components of rehydration solutions for use in 2-D Electrophoresis with GE Healthcare products.
实验方案
Rehydration Solutions
This page describes two-dimensional separation of protein samples with GE Healthcare products.
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