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Key Documents

GE28-4058-46

HiTrap® Capto Adhere

Cytiva 28-4058-46, pack of 5 × 5 mL

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About This Item

分類程式碼代碼:
23151817
NACRES:
NA.56

ligand

N-benzyl-N-methyl ethanolamine

描述

Ion Exchanger Type (value)

包裝

pack of 5 × 5 mL

製造商/商標名

Cytiva 28-4058-46

參數

<20 mL/min flow rate
42 psi

床尺寸

16 mm × 25 mm

床體積

5 mL

柱內徑

16 mm

基質

highly cross-linked agarose

樣品平均尺寸

75 (d₅₀v is the median particle size of the cumulative volume distribution)

cleaning

2-14(pH interval where the medium can be subjected to, for cleaning- or sanitization-in-place.)

工作範圍

3-12(pH interval where the medium can be operated without significant change in function.)

適合性

suitable for bioprocess medium

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一般說明

HiTrap Capto adhere is prepacked with Capto adhere, a multimodal BioProcess ion exchange resin designed to remove contaminats in post-protein A purification. Capto adhere is a strong anion exchanger with multimodal functionality. The multimodal functionality gives a different selectivity compared to traditional anion exchangers. Capto adhere is designed for post-protein A purification of monoclonal antibodies. Removal of leached protein A, aggregates, host cell proteins, nucleic acids, and viruses from monoclonal antibodies is performed in flowthrough mode at which the antibodies pass directly through the column while the contaminants are adsorbed. For optimal performance of Capto adhere, screening/optimization of loading conditions are required.

應用

Protein polishing using Capto Adhere Multimodal chromatography

特點和優勢

  • High capacity and productivity in flowthrough mode.
  • Savings in time and operating costs with a two-step chromatographic process.
  • Wide operational window of pH and conductivity.
  • Prepacked HiTrap columns for easy screening and convenient process development.

儲存和穩定性

Please be aware this product may be shipped 90 days before the expiration date. For more information on the batch specific expiration date, please contact technical service.
Store at 4 to 30 °C (20% Ethanol)

分析報告

To view the Certificate of Analysis for this product, please visit www.cytiva.com.

其他說明

The pressure over the packed bed varies depending on a range of parameters such as the characteristics of the chromatography medium and the column tubing used.

法律資訊

Capto is a trademark of Cytiva
HiTrap is a registered trademark of Cytiva

象形圖

Flame

訊號詞

Warning

危險聲明

儲存類別代碼

3 - Flammable liquids


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