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Key Documents

GE17-1279-02

rProtein A Sepharose Fast Flow

Cytiva 17-1279-02, pack of 25 mL

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About This Item

分類程式碼代碼:
41106500
NACRES:
NA.56

ligand

recombinant protein A (E. coli)

包裝

pack of 25 mL

製造商/商標名

Cytiva 17-1279-02

儲存條件

(20% Ehtanol)

基質

4% cross-linked agarose

粒徑

60-165 μm

平均直徑

90 μm (d50v)

cleaning in place

2-11

工作範圍

3-10

容量

~50 mg binding capacity (human lgG/ml medium)

適合性

suitable for bioprocess medium

儲存溫度

2-8°C

一般說明

rProtein A Sepharose 4 Fast Flow is an affinity resin for antibody purification at laboratory and process scale.

Monoclonal and polyclonal antibody purification

rProtein A Sepharose 4 Fast Flow is built upon the well-established Sepharose Fast Flow platform and is used in many approved monoclonal antibody processes. It is composed of recombinant protein A coupled to the cross-linked 4% agarose base matrix.The highly crosslinked agarose resin enables high flow rates and high productivity.

Protein A resin characteristics

The recombinant protein is produced in E. coli and engineered with an oriented coupling to enhance binding capacity. Epoxy-based coupling ensures low ligand leakage. Specificity of the recombinant protein for the Fc region of IgG is similar to the native protein, giving a high degree of selectivity and yield.

Streamlined scale up

Scale-up with this resin is straightforward and is further aided by a range of prepacked process development tools, making purification scale-up straightforward.

特點和優勢

  • For monoclonal and polyclonal antibody purification at both laboratory and process scale.
  • Well established among Protein A resins as excellent for monoclonal antibody (mAb) processes.
  • Free from animal-derived components.
  • Hydrophilic base matrix ensures low levels of non-specific binding and low levels of host cell-derived impurities in the elution pool.
  • Fulfills industrial demands for security of supply, robust performance, and regulatory support.

儲存和穩定性

Please be aware this product may be shipped 90 days before the expiration date. For more information on the batch specific expiration date, please contact technical service.

分析報告

To view the Certificate of Analysis for this product, please visit www.cytiva.com.

法律資訊

Sepharose is a trademark of Cytiva

象形圖

Flame

訊號詞

Warning

危險聲明

儲存類別代碼

3 - Flammable liquids


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