推荐产品
生物源
mouse
品質等級
共軛
unconjugated
抗體表格
purified antibody
抗體產品種類
primary antibodies
無性繁殖
K-87, monoclonal
分子量
antigen 67 kDa
物種活性
rat, mouse, human
濃度
~1 mg/mL
技術
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:500-1:20,000 (with antigen-retrieval step)
western blot: 1:500-1:20,000 using mouse brain extract
同型
IgG1κ
UniProt登錄號
運輸包裝
dry ice
儲存溫度
−70°C
目標翻譯後修改
unmodified
基因資訊
human ... GAD1(2571)
mouse ... Gad1(14415)
rat ... Gad1(24379)
一般說明
谷氨酸脱羧酶67(GAD67)由基因谷氨酸脱羧酶1(GAD1)编码。GAD1基因位于人染色体2q31.1。GAD67位于树突和细胞体。
特異性
与 GAD67 特异性反应。不与 GAD65 发生交叉反应。
免疫原
来自小鼠 GAD67 的合成肽(氨基酸 87-106)。
该肽与 GAD65 不具有同源性。
應用
小鼠抗谷氨酸脱羧酶67(GAD67)单克隆抗体已被用于:
- 免疫组织荧光
- 蛋白质印迹
- 免疫组织化学。
抗谷氨酸脱羧酶 67(GAD67)单克隆抗体适用于免疫印迹、免疫印迹(1:500-1:20,000 稀释,小鼠脑提取物)和免疫组化(1:500-1:20,000 稀释,小鼠脑切片)。
生化/生理作用
谷氨酸脱羧酶67(GAD67)涉及 γ-氨基丁酸 (GABA)的生产,氨基丁酸是中枢神经系统 (CNS)中的一种抑制性神经递质。GAD67缺乏会导致精神病、精神分裂和双向情感障碍。
外觀
在含有 0.01% 叠氮化钠的磷酸盐缓冲盐水中的溶液。
免責聲明
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
未找到合适的产品?
试试我们的产品选型工具.
儲存類別代碼
10 - Combustible liquids
水污染物質分類(WGK)
nwg
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
其他客户在看
Human molecular genetics, 23(21), 5683-5705 (2014-06-09)
The t(1; 11) translocation appears to be the causal genetic lesion with 70% penetrance for schizophrenia, major depression and other psychiatric disorders in a Scottish family. Molecular studies identified the disruption of the disrupted-in-schizophrenia 1 (DISC1) gene by chromosome translocation
PloS one, 8(6), e66327-e66327 (2013-07-05)
It has been well established that schizophrenia patients display impaired NMDA receptor (NMDAR) functions as well as exacerbation of symptoms in response to NMDAR antagonists. Abnormal NMDAR signaling presumably contributes to cognitive deficits which substantially contribute to functional disability in
Diabetes, 57(5), 1363-1370 (2008-04-01)
We have previously demonstrated that modulation of gamma-aminobutyric acid (GABA) inhibitory tone in the ventromedial hypothalamus (VMH), an important glucose-sensing region in the brain, modulates the magnitude of glucagon and sympathoadrenal responses to hypoglycemia. In the current study, we examined
Cancer medicine, 8(9), 4189-4199 (2019-06-18)
In a previous genome-wide screening, we identified hypermethylated CpG islands around glutamate decarboxylase 1 (GAD1) in lung adenocarcinoma (LADC). In this study, we aimed to investigate the methylation and expression status of GAD1 and its prognostic value in patients with
The Journal of clinical investigation, 126(7), 2482-2494 (2016-06-09)
Major depressive disorder (MDD) is a recurring psychiatric illness that causes substantial health and socioeconomic burdens. Clinical reports have revealed that scopolamine, a nonselective muscarinic acetylcholine receptor antagonist, produces rapid antidepressant effects in individuals with MDD. Preclinical models suggest that
我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门