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形狀
lyophilized powder
比活性
≥30 units/mg protein
成份
Protein, 13-25% modified Warburg-Christian
UniProt登錄號
運輸包裝
dry ice
儲存溫度
−20°C
基因資訊
human ... GPX1(2876)
一般說明
GPX1(谷胱甘肽过氧化物酶 1)属于 GPXs 的四元家族,包括 GPX2、GPX3 和 GPX4。它是一种含硒半胱氨酸的蛋白质。GPX1 是 GPX 酶的主要亚型,广泛存在于细胞内。
注意:在报道的最适 pH 值 8.8 下,我们发现活性约为pH 7.0 时的 10 倍。但是,为了与文献保持一致,避免与 GSH 的非酶催化氧化反应混淆,我们的单位仍在 pH 7.0 下定义。
應用
来自人红细胞的谷胱甘肽过氧化物酶 (GPX) 已被用于测定从皮肤鳞状细胞癌 (CSCC) 或日光性角化病 (SK) 获得的上皮片中过氧化物灭活 GPX 的能力。
生化/生理作用
GPX1(谷胱甘肽过氧化物酶 1)利用还原型谷胱甘肽 (GSH) 作为电子供体,催化多种有机和无机过氧化物的转化。这种酶还负责清除有机和无机过氧化物。
單位定義
在pH7.0,25℃下,一个单元将催化H2O2氧化1.0 μmol的还原型谷胱甘肽至氧化型谷胱甘肽。
外觀
含 25% 蔗糖和 3% 二硫苏糖醇以及磷酸钠缓冲盐的冻干粉
訊號詞
Danger
危險聲明
危險分類
Resp. Sens. 1
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
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