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Merck

G4013

Sigma-Aldrich

谷胱甘肽过氧化物酶 来源于人类红细胞

lyophilized powder, ≥30 units/mg protein

别名:

GSH-Px, 谷胱甘肽:过氧化氢氧化还原酶

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About This Item

CAS号:
MDL號碼:
分類程式碼代碼:
12352204

形狀

lyophilized powder

比活性

≥30 units/mg protein

成份

Protein, 13-25% modified Warburg-Christian

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−20°C

基因資訊

human ... GPX1(2876)

一般說明

GPX1(谷胱甘肽过氧化物酶 1)属于 GPXs 的四元家族,包括 GPX2、GPX3 和 GPX4。它是一种含硒半胱氨酸的蛋白质。GPX1 是 GPX 酶的主要亚型,广泛存在于细胞内。
注意:在报道的最适 pH 值 8.8 下,我们发现活性约为pH 7.0 时的 10 倍。但是,为了与文献保持一致,避免与 GSH 的非酶催化氧化反应混淆,我们的单位仍在 pH 7.0 下定义。

應用

来自人红细胞的谷胱甘肽过氧化物酶 (GPX) 已被用于测定从皮肤鳞状细胞癌 (CSCC) 或日光性角化病 (SK) 获得的上皮片中过氧化物灭活 GPX 的能力。

生化/生理作用

GPX1(谷胱甘肽过氧化物酶 1)利用还原型谷胱甘肽 (GSH) 作为电子供体,催化多种有机和无机过氧化物的转化。这种酶还负责清除有机和无机过氧化物。

單位定義

在pH7.0,25℃下,一个单元将催化H2O2氧化1.0 μmol的还原型谷胱甘肽至氧化型谷胱甘肽。

外觀

含 25% 蔗糖和 3% 二硫苏糖醇以及磷酸钠缓冲盐的冻干粉

象形圖

Health hazard

訊號詞

Danger

危險聲明

危險分類

Resp. Sens. 1

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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