應用
All FSL constructs disperse in biocompatible media and spontaneously and stably incorporate into cell membranes. Cells modified with KODE constructs are known as kodecytes and usually maintain their normal vitality and functionality.
FSL-Lea(tri) has been specifically designed to create live cells (kodecytes) expressing blood group Lea antigens but can also be used to modify other hydrophobic surfaces including fixed cells, virions, and solid phase surfaces. This product can be used to attach reproducible and controlled levels of blood group Lea antigens to erythrocytes. These kodecytes will react with most anti-Lea blood grouping reagents including polyclonal reagents. Lea-kodecytes will also react with monoclonal anti-Leb as these reagents also cross-react with Lea.
FSL-Lea(tri) has been specifically designed to create live cells (kodecytes) expressing blood group Lea antigens but can also be used to modify other hydrophobic surfaces including fixed cells, virions, and solid phase surfaces. This product can be used to attach reproducible and controlled levels of blood group Lea antigens to erythrocytes. These kodecytes will react with most anti-Lea blood grouping reagents including polyclonal reagents. Lea-kodecytes will also react with monoclonal anti-Leb as these reagents also cross-react with Lea.
其他說明
FSL-Lea(tri) is a KODE™ technology construct designed to label hydrophobic surfaces including living cells with Lewis blood group Lea trisaccharide. All KODE FSL constructs consist of three essential designable features: a functional component (F), a spacer (S), and a diacyl lipid (L). FSL-Lea(tri) is comprised of the Lewis blood group Lea trisaccharide Galβ(Fucα4)GlcNAcβ representing F, conjugated via an O(CH2)3NH spacer (SA1) to an activated adipate derivative of dioleoylphosphatidylethanolamine (L1).
法律資訊
KODE Constructs are supplied by KODE Biotech Materials Limited under license from KODE Biotech Limited.
KODE is a trademark of KODE Biotech Ltd.
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
实验方案
FSL Constructs are compounds based on KODE™ technology designed to label hydrophobic surfaces including living cells with carbohydrates, biotin, fluorophores, or 125I.
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