推荐产品
生物源
synthetic
品質等級
形狀
powder
顏色
yellow
mp
256-256 °C
溶解度
formic acid: 50 mg/mL
抗生素活性譜
Gram-positive bacteria
parasites
作用方式
enzyme | inhibits
SMILES 字串
[O-][N+](=O)c1ccc(\C=N\N2CCOC2=O)o1
InChI
1S/C8H7N3O5/c12-8-10(3-4-15-8)9-5-6-1-2-7(16-6)11(13)14/h1-2,5H,3-4H2/b9-5+
InChI 密鑰
PLHJDBGFXBMTGZ-WEVVVXLNSA-N
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相关类别
應用
呋喃唑酮是硝基呋喃衍生物，具有抗原虫和抗菌活性。呋喃唑酮与细菌 DNA 结合，从而导致单胺氧化酶逐渐受到抑制。用于治疗厌食和拮抗家禽对硫胺素的利用 。呋喃唑酮增加鸡心肌细胞中对毒胡萝卜素敏感的 Ca 2+-atp 酶 。
生化／生理作用
呋喃唑酮及其产生的自由基，可能与 DNA 结合并诱导交联。细菌 DNA 对本药特别敏感，从而导致细菌染色体的高水平突变（转换和颠换）。其作用机制使耐药生物体的发展最小化。呋喃唑酮是一种单胺氧化酶 (MAO) 抑制剂，用作 DNA 链间交联剂。
訊號詞
Warning
危險聲明
危險分類
Repr. 2
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
個人防護裝備
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
其他客户在看
B H Ali et al.
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Am J Physiol Heart Circ Physiol. Furazolidone increases thapsigargin-sensitive Ca2+-ATPase in chick cardiac myocytes
D. Lax, R. Martinez-Zaguilan, et al.
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Xi Jin et al.
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Furazolidone (FZD) is an antimicrobial agent that has been shown to have mutagenic, genotoxic and potentially carcinogenic properties when tested in a variety of systems in vitro and in vivo. In this study, we investigated FZD's DNA damaging effect in
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Sequential regimens have been recently reported to be superior to the standard triple therapies in Helicobacter pylori eradication, but most of these studies were performed in Europe and data from developing countries are lacking. So we designed a study to
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