F1678

R-(−)-Fluoxetine hydrochloride

>98% (HPLC), solid

• 别名: (R)-N-Methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propylamine hydrochloride
• 经验公式（希尔记法）: C₁₇H₁₈NOF₃ · HCl
• CAS号: 114247-09-5
• 分子量: 345.79
• MDL號碼: MFCD04040065
• 分類程式碼代碼: 12352200
• PubChem物質ID: 24278433
• NACRES: NA.77

属性

• 品質等級: 100
• 化驗: >98% (HPLC)
• 形狀: solid
• 儲存條件: desiccated
• 顏色: white
• 溶解度: H₂O: soluble >10 mg/mL
• 起源: Eli Lilly
• SMILES 字串: Cl[H].CNCC[C@@H](Oc1ccc(cc1)C(F)(F)F)c2ccccc2
• InChI: 1S/C17H18F3NO.ClH/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20;/h2-10,16,21H,11-12H2,1H3;1H/t16-;/m1./s1
• InChI 密鑰: GIYXAJPCNFJEHY-PKLMIRHRSA-N
• 基因資訊: human ... HTR1A(3350) , HTR1B(3351) , HTR1D(3352) , HTR1E(3354) , HTR1F(3355) , HTR2A(3356) , HTR2B(3357) , HTR2C(3358) , HTR3A(3359) , HTR3B(9177) , HTR3C(170572) , HTR3D(200909) , HTR3E(285242) , HTR4(3360) , HTR5A(3361) , HTR5B(645694) , HTR6(3362) , HTR7(3363)

说明

應用

R-(−)-Fluoxetine hydrochloride has been used as a serotonin reuptake inhibitor:

• to study its effects on the embryoid body (EB) morphogenesis
• in combination with muscimol hydrobromide (MUS) as well as individually to study its neurotoxic effects on neuronal cells grown on multielectrode array (MEA) chips
• to study its effects as an endocrine disruption inducer in Pimephales promelas

生化／生理作用

Fluoxetine exhibits anti-depressant activity by increasing the serotonin levels in the neuron synaptic space. It also exhibits therapeutic effects against depression and other mood disorders.

Selective serotonin reuptake inhibitor.

特點和優勢

This compound was developed by Eli Lilly. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

安全信息

• 象形圖: GHS05,GHS07
• 訊號詞: Danger
• 危險聲明: H302,H315,H318
• 防範說明: P280 - P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338 + P310
• 危險分類: Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: dust mask type N95 (US), Eyeshields, Gloves