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Key Documents

EHU060191

Sigma-Aldrich

MISSION® esiRNA

targeting human FBXO44

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About This Item

分類程式碼代碼:
41105324
NACRES:
NA.51

描述

Powered by Eupheria Biotech

品質等級

產品線

MISSION®

形狀

lyophilized powder

esiRNA cDNA 標靶序列

CTCCTGACTTCGCCCTACTGCATGCAGCCAAATAAAAGGTGTGCCCAGTCTAACCTGTGCCCTGTGGTTTCTGGAAGGAAAGGCAGACTTTAGGTGGTCCTGCCTGGACCTGCAGATGGTACAATGGCATGGCTTCTGTCTAAGGTACAGAGGGGTTGGCATTTCAGGAACCAGGCCATCACAGAAACAGGTTCATGGGCAGACCCCTCAGTGAGCTGCAGGTATCTCACCTGGCAGCCGTCCAGTACTGCTGGCTTCCTCTGGAGGCCCAGCCACAGGCTGGGGTTGGGGTGTGTGGACATCTCTGGGCAGCTCTTGAGTCCACCTTGTGCCAGATCAGCAGTGCCACCCAGGCTCTGCCTCCTGGTGTTACTCTTTGCCAACAGCTTTACGGACATTGGATGAAGCCGAAGCATTTA

Ensembl | 人類登錄號

NCBI登錄號

運輸包裝

ambient

儲存溫度

−20°C

基因資訊

一般說明

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

法律資訊

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

10 - Combustible liquids

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Jia Z Shen et al.
Cell, 184(2), 352-369 (2020-12-29)
Repetitive elements (REs) compose ∼50% of the human genome and are normally transcriptionally silenced, although the mechanism has remained elusive. Through an RNAi screen, we identified FBXO44 as an essential repressor of REs in cancer cells. FBXO44 bound H3K9me3-modified nucleosomes

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