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Merck

E1904

Sigma-Aldrich

Ethyl-3,4-dephostatin

>99% (HPLC), solid

别名:

3,4-Dihydroxy-N-ethyl-N-nitrosoaniline

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About This Item

经验公式(希尔记法):
C8H10N2O3
分子量:
182.18
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77

化驗

>99% (HPLC)

形狀

solid

顏色

brown

溶解度

DMSO: soluble 22 mg/mL
H2O: soluble 8 mg/mL

儲存溫度

2-8°C

SMILES 字串

CCN(N=O)c1ccc(O)c(O)c1

InChI

1S/C8H10N2O3/c1-2-10(9-13)6-3-4-7(11)8(12)5-6/h3-5,11-12H,2H2,1H3

InChI 密鑰

ZTXUSFPBLYQDDN-UHFFFAOYSA-N

生化/生理作用

Stable analog of dephostatin. Selective inhibitor of protein tyrosine phosphatase 1B and SHPTP-1. Does not inhibit CD45-associated phosphatases.

特點和優勢

This compound is featured on the Phosphoprotein Phosphatases (Tyrosine) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

注意

Store under nitrogen

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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J H Kim et al.
Cell death & disease, 4, e588-e588 (2013-04-13)
Hypoxia enhances the proliferation and migration of adipose-derived stem cells (ASCs) via the generation of reactive oxygen species (ROS). Therefore, this study primarily investigated whether or not ROS generation could regulate microRNA-210 (miR-210) expression, and increase proliferation/migration of ASCs. In

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