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Merck
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Key Documents

E1625

Sigma-Aldrich

弹性蛋白 来源于牛颈部韧带

powder

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About This Item

CAS号:
EC號碼:
MDL號碼:
分類程式碼代碼:
12352202
NACRES:
NA.61

生物源

bovine neck ligament

品質等級

形狀

powder

UniProt登錄號

儲存溫度

2-8°C

InChI

1S/C27H48N6O6/c1-9-17(6)23(32-24(36)19(13-15(2)3)30-18(7)34)26(38)29-14-21(35)31-22(16(4)5)27(39)33-12-10-11-20(33)25(37)28-8/h15-17,19-20,22-23H,9-14H2,1-8H3,(H,28,37)(H,29,38)(H,30,34)(H,31,35)(H,32,36)/t17-,19-,20-,22-,23-/m0/s1

InChI 密鑰

DPUYCSDGMSDKKV-MKBYFEBXSA-N

基因資訊

cow ... ELN(280781)

應用

弹性蛋白是一种结构蛋白,已用于研究慢性阻塞性肺疾病(COPD)。它可能用于调查COPD患者缺乏对这些蛋白质的修复的原因。
由于其增溶的几种策略,目前发现高度稳定且具有血液相容性的蛋白质可用于构建生物材料。

生化/生理作用

负责许多组织弹性的蛋白质它在血管中尤其重要,因为它占干组织重量的 50%。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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H M Morrison et al.
Biochimica et biophysica acta, 1430(2), 179-190 (1999-03-20)
Solubilization of elastin by human leukocyte elastase (HLE) cannot be analyzed by conventional kinetic methods because the biologically relevant substrate is insoluble and the concentration of enzyme-substrate complex has no physical meaning. We now report quantitative measurements of the binding
N Vyavahare et al.
The American journal of pathology, 155(3), 973-982 (1999-09-17)
Elastin, an abundant structural protein present in the arterial wall, is prone to calcification in a number of disease processes including porcine bioprosthetic heart valve calcification and atherosclerosis. The mechanisms of elastin calcification are not completely elucidated. In the present
Isabella C P Rodrigues et al.
Scientific reports, 12(1), 5230-5230 (2022-03-30)
Vascular graft surgeries are often conducted in trauma cases, which has increased the demand for scaffolds with good biocompatibility profiles. Biodegradable scaffolds resembling the extracellular matrix (ECM) of blood vessels are promising vascular graft materials. In the present study, polyurethane
Mervyn J Merrilees et al.
Respiratory research, 9, 41-41 (2008-05-20)
COPD is characterised by loss of alveolar elastic fibers and by lack of effective repair. Elastic fibers are assembled at cell surfaces by elastin binding protein (EBP), a molecular chaperone whose function can be reversibility inhibited by chondroitin sulphate of
Pro-inflammatory phenotype of COPD fibroblasts not compatible with repair in COPD lung.
Zhang J., et al.
Journal of Cellular and Molecular Medicine (2011)

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