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化驗
≥98% (HPLC)
形狀
powder
溶解度
DMSO: >10 mg/mL
H2O: insoluble
抗生素活性譜
Gram-negative bacteria
Gram-positive bacteria
parasites
作用方式
DNA synthesis | interferes
SMILES 字串
CCCCCCCCCCCC1=C(O)C(=O)C=C(O)C1=O
InChI
1S/C17H26O4/c1-2-3-4-5-6-7-8-9-10-11-13-16(20)14(18)12-15(19)17(13)21/h12,18,21H,2-11H2,1H3
InChI 密鑰
IRSFLDGTOHBADP-UHFFFAOYSA-N
基因資訊
human ... XIAP(331)
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一般說明
恩贝酸是一种天然的苯醌衍生物，最早从白花酸滕果植物中提取。它在结构上类似于泛醌。
應用
使用恩贝酸：
- 研究其对活化T细胞(NFATc1)荧光素酶活性的核因子kB配体(RANKL)诱导的核因子的受体激活剂的影响
- 研究其在介导帕金森病(PD)机制中的作用′
- 治疗全鼠胚胎，以确定其对X连锁抑制细胞凋亡蛋白(XIAP)活性的影响
生化／生理作用
恩贝酸具有抗氧化、线粒体解耦联和抗生育特性。它还具有抗糖尿病、抗惊厥、抗焦虑和抗微生物活性等作用。恩贝酸是一种有效的神经保护剂，也可作为脑卒中的辅助治疗。
恩贝酸（Embelin）是XIAP（X连锁凋亡抑制蛋白）的抑制剂；体内抗肿瘤和抗炎活性。
訊號詞
Warning
危險聲明
危險分類
Repr. 2
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
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Overexpression of the androgen receptor (AR) and anti-apoptotic genes including X-linked inhibitor of apoptosis protein (XIAP) provide tumors with a proliferative advantage. Therefore, our objective was to determine whether novel antiandrogen (CBDIV17) and XIAP inhibitor based combination therapy can treat
Sekar Mahendran et al.
Chemical & pharmaceutical bulletin, 59(8), 913-919 (2011-08-02)
Antioxidant and related properties of the plant Embelia ribes and embelin are well known. In the present study embelin was condensed with various aromatic substituted primary amines to yield ten new and one reported derivatives along with monomethyl embelin. All
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