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Merck

E1283

Sigma-Aldrich

ERK2,活性,GST 标记 人

recombinant, expressed in E. coli, PRECISIO® Kinase, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

别名:

ERT1, MAPK1, MAPK2, P41mapk, P42MAPK, PRKM1, PRKM2, p40, p47

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About This Item

分類程式碼代碼:
12352200
NACRES:
NA.32

重組細胞

expressed in E. coli

品質等級

產品線

PRECISIO® Kinase

化驗

≥70% (SDS-PAGE)

形狀

buffered aqueous glycerol solution

比活性

613-829 nmol/min·mg

分子量

~68 kDa

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−70°C

基因資訊

human ... MAPK1(5594)

生化/生理作用

ERK2 is a protein serine/threonine kinase that is a member of the extracellular signal-regulated kinases (ERKs) which are activated in response to numerous growth factors and cytokines. Activation of ERK2 requires both tyrosine and threonine phosphorylation that is mediated by MEK. ERK2 is ubiquitously distributed in tissues with the highest expression in heart, brain and spinal cord. Activated ERK2 translocates into the nucleus where it phosphorylates various transcription factors (e.g., Elk-1, c-Myc, c-Jun, c-Fos, and C/EBP beta).

外觀

Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.2 5mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.

法律資訊

PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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