D4072

Delta Sleep Inducing Peptide

• 别名: DSIP, Emideltide, Sleep inducing peptide, Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu
• 经验公式（希尔记法）: C₃₅H₄₈N₁₀O₁₅
• CAS号: 62568-57-4
• 分子量: 848.81
• MDL號碼: MFCD00076883
• 分類程式碼代碼: 12352200
• PubChem物質ID: 329798794
• NACRES: NA.32

属性

• 形狀: powder
• 儲存溫度: −20°C
• SMILES 字串: C[C@H](NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(=O)NCC(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(O)=O
• InChI: 1S/C35H48N10O15/c1-16(41-32(56)20(36)9-18-11-37-21-6-4-3-5-19(18)21)30(54)39-12-25(47)38-13-26(48)44-23(10-29(52)53)34(58)42-17(2)31(55)45-24(15-46)33(57)40-14-27(49)43-22(35(59)60)7-8-28(50)51/h3-6,11,16-17,20,22-24,37,46H,7-10,12-15,36H2,1-2H3,(H,38,47)(H,39,54)(H,40,57)(H,41,56)(H,42,58)(H,43,49)(H,44,48)(H,45,55)(H,50,51)(H,52,53)(H,59,60)/t16-,17-,20-,22-,23-,24-/m0/s1
• InChI 密鑰: ZRZROXNBKJAOKB-GFVHOAGBSA-N

说明

Amino Acid Sequence

Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu-OH

一般說明

Delta sleep inducing peptide (DSIP) is a nonapeptide which was isolated from the rabbit brain. It is synthesized in the hypothalamus and is present in small amounts in the blood.

生化／生理作用

DSIP promotes sleep by targeting various areas of the brain. The peptide is easily absorbed from the gut and is not denatured by enzymes. It crosses the blood-brain barrier easily. DSIP influences the circadian rhythm in humans. Low concentrations of the peptide are observed in patients with schizophrenia and depression.

安全信息

• 儲存類別代碼: 13 - Non Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable