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Merck

D2631

Sigma-Aldrich

双十六烷基磷酸酯

别名:

DHP, 磷酸二鲸蜡酯

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About This Item

线性分子式:
[CH3(CH2)15O]2P(O)OH
CAS号:
分子量:
546.85
Beilstein:
1717117
EC號碼:
MDL號碼:
分類程式碼代碼:
51191904
PubChem物質ID:
NACRES:
NA.25

描述

anionic

品質等級

形狀

powder

分子量

546.85 g/mol

技術

DNA extraction: suitable

mp

74-75 °C (lit.)

脂質類型

phospholipids

儲存溫度

−20°C

SMILES 字串

OP(OCCCCCCCCCCCCCCCC)(OCCCCCCCCCCCCCCCC)=O

InChI

1S/C32H67O4P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-35-37(33,34)36-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h3-32H2,1-2H3,(H,33,34)

InChI 密鑰

RNPXCFINMKSQPQ-UHFFFAOYSA-N

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生化/生理作用

磷酸二十六烷基酯(DHP)是带负电荷的脂质,用于形成模型膜。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Hamdy Abdelkader et al.
Journal of pharmaceutical sciences, 100(5), 1833-1846 (2011-01-20)
This study aimed at preparing and evaluating Span 60-based niosomes for ocular delivery of naltrexone hydrochloride (NTX). Selected charged lipids [dicetyl phosphate (DCP) and stearyl amine (STA)] and surfactants [poly-24-oxyethylene cholesteryl ether (C24) and sodium cholate (CH)] were investigated as
Haruyuki Ishii et al.
Colloids and surfaces. B, Biointerfaces, 92, 372-376 (2011-12-16)
Hollow silica particle was obtained with a vesicle template synthesis in water under ambient conditions in the presence of ammonia. Biomimetic vesicles, liposomes were used, which consisted of a zwitterionic phospholipid, 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC), and a tiny amount of charged amphiphiles
Abbas Pardakhty et al.
International journal of pharmaceutics, 328(2), 130-141 (2006-09-26)
In this study, niosomes of polyoxyethylene alkyl ethers (Brij) were prepared for encapsulation of insulin by film hydration method. Without cholesterol, brij 35 and brij 58 did not form niosomes, apparently because of relatively large polar head groups in comparison
Laurent Salade et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 129, 257-266 (2018-06-15)
The nose-to-brain delivery of ghrelin loaded in liposomes is a promising approach for the management of cachexia. It could limit the plasmatic degradation of ghrelin and provide direct access to the brain, where ghrelin's specific receptors are located. Anionic liposomes
Mahmoud Mokhtar et al.
International journal of pharmaceutics, 361(1-2), 104-111 (2008-06-26)
Proniosomal gels or solutions of flurbiprofen were developed based on span 20 (Sp 20), span 40 (Sp 40), span 60 (Sp 60), and span 80 (Sp 80) without and with cholesterol. Nonionic surfactant vesicles (niosomes) formed immediately upon hydrating proniosomal

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