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品質等級
化驗
≥98% (HPLC)
形狀
solid
儲存條件
desiccated
under inert gas
顏色
yellow
溶解度
DMSO: ~6.8 mg/mL
H2O: insoluble
儲存溫度
2-8°C
SMILES 字串
Clc1cccc(\C=N\N=C\c2cccc(Cl)c2)c1
InChI
1S/C14H10Cl2N2/c15-13-5-1-3-11(7-13)9-17-18-10-12-4-2-6-14(16)8-12/h1-10H/b17-9+,18-10+
InChI 密鑰
XMOVWXSCYLINBJ-BEQMOXJMSA-N
生化／生理作用
3,3′-二氯苯甲醛嗪（DCB）可用作具有中性协同作用的变构配体。在3,3′-二氟苯甲醛嗪（DFB）的帮助下，它可以阻断mGluRs（代谢型谷氨酸受体亚型5（mGluR5））的正向别构调节作用，以及3,3′-二甲氧基苯甲醛嗪（DMeOB）的负调节作用。
代谢型谷氨酸受体mGluR5的中性别构调节剂。
特點和優勢
该化合物是《受体分类及信号转导》手册上谷氨酸受体（G蛋白家族）页面上的特色化合物。想要浏览手册的其他页面， 请单击此处。
訊號詞
Danger
危險分類
Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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Mitogen-activated protein kinases (MAPK) signaling affects many processes, some of which have different outcomes in the same cell. In Arabidopsis, activation of a MAPK cascade consisting of YODA, MKK4/5 and MPK3/6 inhibits early stages of stomatal developmental, but the ability
Yvonne Bausback et al.
Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists, 24(4), 459-467 (2017-06-01)
To evaluate the performance of the Ranger paclitaxel-coated balloon vs uncoated balloon angioplasty for femoropopliteal lesions. Between January 2014 and October 2015, the prospective, randomized RANGER SFA study ( ClinicalTrials.gov identifier NCT02013193) enrolled 105 patients with symptomatic lower limb ischemia
A family of highly selective allosteric modulators of the metabotropic glutamate receptor subtype 5
O'Brien JA, et al.
Molecular Pharmacology, 64(3), 731-740 (2003)
Dieuwertje Van der Does et al.
PLoS genetics, 13(6), e1006832-e1006832 (2017-06-13)
Plants actively perceive and respond to perturbations in their cell walls which arise during growth, biotic and abiotic stresses. However, few components involved in plant cell wall integrity sensing have been described to date. Using a reverse-genetic approach, we identified
Binrui Xu et al.
Scientific reports, 7, 45079-45079 (2017-03-25)
Poly(3,4-ethylenedioxythiophene):poly(styrene sulfonate) (PEDOT:PSS) is most commonly used as an anode buffer layer in bulk-heterojunction (BHJ) polymer solar cells (PSCs). However, its hygroscopic and acidic nature contributes to the insufficient electrical conductivity, air stability and restricted photovoltaic (PV) performance for the
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