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Merck

D0162

Sigma-Aldrich

地丹诺辛

≥98% (HPLC)

别名:

ddI, ddIno

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About This Item

经验公式(希尔记法):
C10H12N4O3
CAS号:
分子量:
236.23
Beilstein:
3619529
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.55

品質等級

化驗

≥98% (HPLC)

形狀

powder

儲存溫度

−20°C

SMILES 字串

OC[C@@H]1CC[C@@H](O1)n2cnc3C(=O)NC=Nc23

InChI

1S/C10H12N4O3/c15-3-6-1-2-7(17-6)14-5-13-8-9(14)11-4-12-10(8)16/h4-7,15H,1-3H2,(H,11,12,16)/t6-,7+/m0/s1

InChI 密鑰

BXZVVICBKDXVGW-NKWVEPMBSA-N

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生化/生理作用

核苷酸拮抗剂

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Gilles Casano et al.
Bioorganic & medicinal chemistry, 18(16), 6012-6023 (2010-07-20)
In our search for potent anti-HIV and antiplasmodial agents, novel series of flavonoid derivatives and their chalcone intermediates were synthesized and evaluated for inhibition of HIV multiplication and antiproliferative activity on Plasmodium falciparum parasites. Chalcones exhibited a more selective antiplasmodial
Alejandro Arenas-Pinto et al.
Antiviral therapy, 17(2), 275-282 (2012-02-02)
Genetic predisposition to dideoxynucleoside-induced mitochondrial dysfunction might be related to mitochondrial DNA (mtDNA) polymorphisms. Severe hyperlactataemia is probably the best model to assess such a predisposition. For this exploratory study in White European and Black African HIV-infected adults, hypervariable region
Yue-Ping Wang et al.
European journal of medicinal chemistry, 44(3), 1016-1023 (2008-08-12)
A series of new 5-alkyl-2-benzylsulfanylpyrimidin-4(3H)-ones (5a-y) bearing different substituted arylmethyl moieties at the C-6 position of the pyrimidine core have been synthesized and evaluated for their in vitro activities against HIV-1 and HIV-2 in MT-4 cell cultures. The majority of
J N L Schouten et al.
Alimentary pharmacology & therapeutics, 36(9), 875-885 (2012-09-14)
Idiopathic noncirrhotic portal hypertension (INCPH) has been reported increasingly in patients with HIV infection. To evaluate the number of nationwide diagnosed HIV-associated INCPH cases and to assess its clinical features, risk factors and outcome. All HIV centres in the Netherlands
Elizabeth Ojewole et al.
Planta medica, 78(4), 354-361 (2011-12-14)
The buccal mucosal route offers several advantages but the delivery of certain drugs can be limited by low membrane permeability. This study investigated the buccal permeability properties of didanosine (ddI) and assessed the potential of Aloe vera gel (AVgel) as

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