C9672

Monoclonal Anti-Neural Cell Adhesion Molecule antibody produced in mouse

clone NCAM-0B11, ascites fluid

• 别名: Anti-CD56-CY, Anti-NCAM
• MDL號碼: MFCD00164707
• 分類程式碼代碼: 12352203
• NACRES: NA.41

属性

• 生物源: mouse
• 品質等級: 200
• 共軛: unconjugated
• 抗體表格: ascites fluid
• 抗體產品種類: primary antibodies
• 無性繁殖: NCAM-0B11, monoclonal
• 分子量: antigen 140-180 kDa
• 包含: 15 mM sodium azide
• 物種活性: rat, human
• 技術: immunocytochemistry: suitable using cells and tissues; western blot: 1:100 using a freshly prepared extract from newborn and adult rat brain, or rat cerebral cortex extract
• 同型: IgG1
• UniProt登錄號: O15394; P13591
• 運輸包裝: dry ice
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... NCAM1(4684) , NCAM2(4685) ; rat ... Ncam1(24586) , Ncam2(288280)

说明

一般說明

Monoclonal Anti-N-CAM (mouse IgG1 isotype) is derived from the hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse. Neural cell adhesion molecule (N-CAM), the best characterized CAM, exists in adult brain. It belongs to the family of sialoglycoproteins, which arise from alternative splicing of mRNA transcribed from a single gene. Immunocytochemical data indicate that in the adult, N-CAM is expressed mainly in cells of the nervous system. There are indications that N-CAM may also be expressed by non-neural cells in the adult, as it has been found in studies of various embryonic developmental stages.

Mouse monoclonal clone NCAM-0B11 anti-Neural Cell Adhesion Molecule antibody localizes the high molecular weight isoform of N-CAM (neural cell adhesion molecule) in human and several other mammalian species. The antibody shows a strong reaction to N-CAM A/N-CAM 180, however it also recognizes N-CAM B/N-CAM 140. In an immunoblot, the product reacts with polysialated N-CAM in embryonic material. Breakdown products of N-CAM may be stained; they appear as bands lower than 100 kD on the immunoblot.

免疫原

growth cone enriched plasma membrane fraction from E17 rat forebrain.

應用

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunofluorescence (1 paper)
Immunohistochemistry (3 papers)

Monoclonal Anti-Neural Cell Adhesion Molecule antibody produced in mouse has been used in:

• Immunofluorescence
• Immunohistochemistry
• Immunoblotting

生化／生理作用

Neural cell adhesion molecule (N-CAM) are believed to be involved in cell-cell interactions and probably play an important role in embryogenesis and development.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全信息

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: nwg
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable