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About This Item
经验公式（希尔记法）:
C16H19N3O4S
CAS号:
分子量:
349.40
MDL號碼:
分類程式碼代碼:
51282517
PubChem物質ID:
NACRES:
NA.85
推荐产品
化驗
≥90.0% (Cephradine, HPLC)
形狀
powder
溶解度
ethanol: practically insoluble 96%
hexane: practically insoluble
water: slightly soluble
抗生素活性譜
Gram-negative bacteria
Gram-positive bacteria
作用方式
cell wall synthesis | interferes
儲存溫度
2-8°C
SMILES 字串
[H][C@]12SCC(C)=C(N1C(=O)[C@H]2NC(=O)[C@H](N)C3=CCC=CC3)C(O)=O
InChI
1S/C16H19N3O4S/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)10(17)9-5-3-2-4-6-9/h2-3,6,10-11,15H,4-5,7,17H2,1H3,(H,18,20)(H,22,23)/t10-,11-,15-/m1/s1
InChI 密鑰
RDLPVSKMFDYCOR-UEKVPHQBSA-N
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一般說明
Chemical structure: ß-lactam
應用
Cefradin was used to study the effect of expression, binding, and inhibition of PBP3 and other penicillin-binding proteins (PBPs) on bacterial cell wall mucopeptide synthesis.
生化／生理作用
Cefradin is a semi-synthetic cephalosporin that inhibits the last stage of bacterial cell wall synthesis by binding to certain penicillin-binding proteins (PBPs), such as PBP3, which results in cell lysis. Cell lysis is mediated by bacterial cell wall autolytic enzymes. It is effective against Gram-positive and Gram-negative bacteria. Cefradin may also interfere with autolysin inhibitors.
其他說明
Keep container tightly closed in a dry and well-ventilated place.
訊號詞
Danger
危險分類
Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
其他客户在看
Antioxidative responses of Pseudomonas fluorescens YZ2 to simultaneous exposure of Zn and Cefradine.
Yan-Bin Xu et al.
Ecotoxicology (London, England), 24(7-8), 1788-1797 (2015-07-05)
Binary pollution of both heavy metals and antibiotics has received increasing attentions for their joint effects of eco-toxicity and health hazards. To reveal the effects of mixtures of different pollutants on bacterial antioxidant response system, Pseudomonas fluorescens ZY2, a new
Characteristics of Streptococcus pyogenes strains isolated from Chinese children with scarlet fever.
Yunmei Liang et al.
Acta paediatrica (Oslo, Norway : 1992), 97(12), 1681-1685 (2008-08-12)
To analyse the characteristics of Streptococcus pyogenes isolates from Chinese children with scarlet fever. Minimal inhibitory concentration with nine antibiotics was performed on 145 Streptococcus pyogenes isolates acquired from Beijing and Shanghai in 2007. Their macrolide-resistant genes (mefA, ermB and
James R Adams et al.
The British journal of oral & maxillofacial surgery, 46(8), 673-674 (2008-05-20)
Dental infections are associated with a range of serious complications. The orofacial region provides potential spaces in the tissue that infections of dental origin can occupy. We describe the subtemporal extension of a dental infection, the late development of cranial
Men-Tai Wu et al.
The Annals of pharmacotherapy, 44(10), 1673-1676 (2010-09-03)
To report a case of cephalosporin-induced factor V inhibitor development, an uncommon but potentially fatal condition characterized by severe hemorrhage. A 71-year-old Chinese man presented with factor V inhibitors after a 7-day cephradine course for a urinary tract infection, characterized
J Q Chen et al.
Journal of hazardous materials, 209-210, 520-523 (2012-02-07)
Two common freshwater algae Microcystis aeruginosa and Scenedesmus obliquus were employed as test organism to evaluate the toxic effects of the widely used antibiotic, cefradine. In general, cefradine had significantly toxic effect on population growth and chlorophyll-a accumulation of two
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