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C5174

Sigma-Aldrich

4'-氯地西泮

≥98% (TLC)

别名:

7-氯-5-（4-氯苯基）-1,3-二氢-1-甲基-2H-1,4-苯二氮卓-2-酮, Ro 5-4864, Ro5-4864

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About This Item

经验公式（希尔记法）:
C16H12Cl2N2O
CAS号:
14439-61-3
分子量:
319.19
Beilstein:
685202
MDL號碼:
MFCD00043406
分類程式碼代碼:
12352200
PubChem物質ID:
24892765
NACRES:
NA.77

品質等級

200

化驗

≥98% (TLC)

形狀

powder

藥物控制

regulated under CDSA - not available from Sigma-Aldrich Canada

溶解度

2-hydroxypropyl-β-cyclodextrin: insoluble
H2O: insoluble

SMILES 字串

O=C1CN=C(C2=CC=C(Cl)C=C2)C3=CC(Cl)=CC=C3N1C

InChI

1S/C16H12Cl2N2O/c1-20-14-7-6-12(18)8-13(14)16(19-9-15(20)21)10-2-4-11(17)5-3-10/h2-8H,9H2,1H3

InChI 密鑰

PUMYFTJOWAJIKF-UHFFFAOYSA-N

基因資訊

rat ... Tspo(24230)

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應用

4′-氯地西泮在线粒体功能研究中用作转运蛋白配体。此外，也用于研究其对葡萄糖缺失T98G星形胶质细胞的保护作用。

生化／生理作用

4'-氯二氮卓酮 (Ro5-4864) 是线粒体转运蛋白 18 kDa (TSPO) 的强效选择性配体，以前称为外周苯二氮卓类受体 (PBR)。Ro5-4864 不与 GABA (A) 受体结合，缺乏典型的苯二氮卓类效应，但在多项研究中发现其具有神经保护作用。

象形圖

Exclamation mark
GHS07

訊號詞

Warning

危險聲明

H302

危險分類

Acute Tox. 4 Oral

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
078M4154V
13180316
018M4025V
106M4099V
014M4087V

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