所有图片(2)
About This Item
经验公式（希尔记法）:
C18H12CrN3O6
CAS号:
分子量:
418.30
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.25
推荐产品
生物源
synthetic
品質等級
化驗
≥98% (HPLC)
形狀
powder
損耗
≤5% loss on drying
儲存溫度
room temp
SMILES 字串
O=C(O[Cr](OC(=O)c1ccccn1)OC(=O)c2ccccn2)c3ccccn3
InChI
1S/3C6H5NO2.Cr/c3*8-6(9)5-3-1-2-4-7-5;/h3*1-4H,(H,8,9);/q;;;+3/p-3
InChI 密鑰
CBDQOLKNTOMMTL-UHFFFAOYSA-K
一般說明
吡啶甲酸铬是2型糖尿病的补充或替代药物，是抗胰岛素的3T3-L1脂肪细胞中CrPic的抗糖尿病机制。
應用
吡啶羧酸铬 (CrPic) 是一种膳食补充剂，可用于研究其作为葡萄糖摄取和胰岛素活性调节剂的潜力。CrPic用于研究其对动物体内核因子-κB（NF-κB）和核因子-E2相关因子-2（Nrf2）传递的影响。
生化／生理作用
吡啶甲酸铬（CrPic）是2型糖尿病的补充或替代药物。 实验证据表明，CrPic通过激活p38 MAPK对葡萄糖摄取产生影响。铬被认为可以增强胰岛素的作用，从而导致2型糖尿病的胰岛素敏感性增加。
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
E A Ott et al.
Journal of animal science, 77(11), 3022-3030 (1999-11-24)
Thoroughbred and Quarter Horse yearlings (n = 24; 335+/-7 d of age) were used in a 112-d feeding trial to determine whether chromium (Cr) supplementation would alter growth, development, and energy metabolism of growing horses on high-concentrate diets. The horses
L R Gentry et al.
Journal of animal science, 77(5), 1284-1294 (1999-05-26)
Thirty-two Suffolk wether lambs were fed for 84 d in a 2 x 2 factorial experiment using two levels of dietary protein (9.0 to 12.1% CP, low protein, LP; or 12.8 to 14.4% CP, high protein, HP) and supplemental Cr
M D Lindemann et al.
Journal of animal science, 82(10), 2972-2977 (2004-10-16)
A cooperative research study involving 353 litters was conducted at three stations to determine the effects of graded levels of supplemental Cr from chromium tripicolinate (CrPic) on reproductive performance of sows and preweaning performance of their pigs. Primiparous and multiparous
T L Ward et al.
Journal of animal science, 75(4), 1001-1008 (1997-04-01)
An experiment was conduct to determine the interactive effects of dietary chromium tripicolinate (CrPic), CP, and pen space (PS) as a stress on growth performance, carcass traits, and plasma hormones and metabolites of crossbred growing-finishing pigs (128 pigs; initial BW
D J Appleton et al.
Journal of feline medicine and surgery, 4(1), 13-25 (2002-03-01)
The effect of dietary chromium supplementation on glucose and insulin metabolism in healthy, non-obese cats was evaluated. Thirty-two cats were randomly divided into four groups and fed experimental diets consisting of a standard diet with 0 ppb (control), 150 ppb
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