推荐产品
产品名称
L -肉碱 内盐, synthetic, ≥98%
生物源
synthetic
品質等級
化驗
≥98%
形狀
powder
顏色
white
mp
197-212 °C (lit.)
應用
cell analysis
detection
SMILES 字串
C[N+](C)(C)C[C@H](O)CC([O-])=O
InChI
1S/C7H15NO3/c1-8(2,3)5-6(9)4-7(10)11/h6,9H,4-5H2,1-3H3/t6-/m1/s1
InChI 密鑰
PHIQHXFUZVPYII-ZCFIWIBFSA-N
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相关类别
應用
L-肉碱内盐已被用作Seahorse XF线粒体应激测定中的测定培养基的组分。它还被口服给予荷瘤小鼠，以研究其对过氧化物酶体增殖物激活受体的调节作用，从而对肝脏炎症反应进行分析。
生化／生理作用
肉碱由赖氨酸生物合成。肉碱可促进脂肪酸转运至线粒体区室中。在骨骼肌和心肌组织中，它充当代谢辅助因子。肉碱可能与支链氨基酸的能量产生有关。
肉毒碱是一种天然存在于大多数哺乳动物组织中的季铵。它在骨骼肌和心脏中参与能量代谢调控，浓度相对较高。它可将葡萄糖代谢由糖酵解转移至糖原储存，并促进长链脂肪酸向线粒体转运，使其在线粒体氧化产生能量。
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
其他客户在看
Sunil K Panchal et al.
Food & function, 6(8), 2496-2506 (2015-07-21)
Obesity and dyslipidaemia are metabolic defects resulting from impaired lipid metabolism. These impairments are associated with the development of cardiovascular disease and non-alcoholic fatty liver disease. Correcting the defects in lipid metabolism may attenuate obesity and dyslipidaemia, and reduce cardiovascular
L-carnitine ameliorates the liver inflammatory response by regulating carnitine palmitoyltransferase I-dependent PPAR? signaling
Fang Jiang
Molecular Medicine Reports, 13(2) (2015)
Development of a high-throughput method for real-time assessment of cellular metabolism in intact long skeletal muscle fibre bundles
Rui Li
The Journal of Physiology, 594(24), 7197-7213 (2016)
N A Oey et al.
Placenta, 27(8), 841-846 (2005-11-23)
Carnitine plays an indispensable role in fatty acid oxidation. Previous studies revealed that fetal carnitine is derived from the mother via transplacental transfer. Recent studies demonstrated the presence and importance of an active fatty acid oxidation system in the human
Andrea Lenzi et al.
Fertility and sterility, 81(6), 1578-1584 (2004-06-15)
To determine the efficacy of combined l-carnitine and l-acetyl-carnitine therapy in infertile males with oligo-astheno-teratozoospermia. Placebo-controlled double-blind randomized trial. University tertiary referral center. Sixty infertile patients (aged 20-40 years) with the following baseline sperm selection criteria: concentration, 10 to 40
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