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Merck
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主要文件

B8556

Sigma-Aldrich

血蓝蛋白 来源于软体动物

buffered aqueous solution

别名:

Blue 载体®

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About This Item

CAS号:
MDL號碼:
分類程式碼代碼:
12352202
NACRES:
NA.56

生物源

Concholepas sp. (Concholepas concholepas )

品質等級

形狀

buffered aqueous solution

技術

bioconjugation: suitable

儲存溫度

2-8°C

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應用

Blue Carrier是一种从软体动物智利鲍鱼的血淋巴中分离得到的载氧蛋白。它具有高度的免疫原性,可用作产生小分子抗体的载体蛋白。该方案的一个例子是关于肌胃糜烂素抗体的生产。
血蓝蛋白是用于抗体生产的载体蛋白。在膀胱癌的治疗中,它用于促进半抗原和肽抗体的生产,是癌症疫苗的一中成分。

生化/生理作用

用于抗体生产的高可溶性载体蛋白

外觀

100 mg溶于0.5 mL 0.15 M NaCl、0.1 M磷酸钠,pH 7.2

法律資訊

Blue Carrier is a registered trademark of Biosonda S.A.

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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Harold Oliva et al.
Hybridoma and hybridomics, 21(5), 365-374 (2002-12-10)
We studied the reactivity of mouse monoclonal antibodies (MAbs) against the hemocyanin from the Chilean marine gastropod Concholepas concholepas (CCH). This protein has been successfully used as a carrier to produce antibodies to haptens and peptides. All MAbs (13) belonging
M I Becker et al.
Hybridoma, 17(4), 373-381 (1998-10-28)
This study is the first report of the development of monoclonal antibodies (MAbs) against gizzerosine (GZ), one of the causative agents of black vomit, a serious poultry disease. Balb/c mice were immunized with different GZ conjugates; the most immunogenic conjugate
Bruno Moltedo et al.
The Journal of urology, 176(6 Pt 1), 2690-2695 (2006-11-07)
We determined the antitumor properties of a newly available hemocyanin obtained from the Chilean gastropod Concholepas concholepas (Biosonda Corp., Santiago, Chile) in a syngeneic heterotopic mouse bladder carcinoma model. Since keyhole limpet hemocyanin (Pierce, Rockford, Illinois) is used increasingly in
Enhanced structural stability of Concholepas hemocyanin increases its immunogenicity and maintains its non-specific immunostimulatory effects.
Arancibia S., et al.
European Journal of Immunology (2011)
Anaphylaxis caused by hemocyanin contained in shrimp cephalothorax.
Daiana Guillen et al.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 113(6), 674-675 (2014-10-14)

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