推荐产品
生物源
Penicillium brefeldianum
品質等級
等級
for molecular biology
產品線
BioXtra
化驗
≥99% (HPLC and TLC)
形狀
powder
分子量
280.36
溶解度
DMSO: 10 mg/mL (Store stock solutions at -20 °C)
抗生素活性譜
neoplastics
作用方式
protein synthesis | interferes
儲存溫度
2-8°C
SMILES 字串
C[C@H]1CCC\C=C\[C@@H]2C[C@H](O)C[C@H]2[C@H](O)\C=C\C(=O)O1
InChI
1S/C16H24O4/c1-11-5-3-2-4-6-12-9-13(17)10-14(12)15(18)7-8-16(19)20-11/h4,6-8,11-15,17-18H,2-3,5,9-10H2,1H3/b6-4+,8-7+/t11-,12+,13-,14+,15+/m0/s1
InChI 密鑰
KQNZDYYTLMIZCT-KQPMLPITSA-N
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一般說明
化学结构:大环内酯
布雷菲德菌素可诱导CtBP1/BARS蛋白的ADP核糖基化,从而调节胞内运输和分泌蛋白从内质网到高尔基体的运动。
應用
适用于分泌蛋白和细胞内转运机制的分子生物学研究
生化/生理作用
布雷菲德菌素A(BFA)是一种会破坏高尔基体的结构和功能的真菌代谢产物。BFA是鞘磷脂循环的一种激活剂。已在人类肿瘤细胞中观察到了布雷菲德菌素A介导的细胞凋亡。
原則
布雷菲德菌素是一种真菌代谢产物,可通过破坏高尔基体来破坏真核细胞中的蛋白质分泌。它不会影响蛋白质合成过程。
訊號詞
Danger
危險聲明
防範說明
危險分類
Acute Tox. 3 Oral
儲存類別代碼
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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