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Merck

B4679

Sigma-Aldrich

BIS-TRIS丙烷

BioPerformance Certified, suitable for cell culture, ≥99.0%

别名:

1,3-双[三(羟甲基)甲氨基]丙烷

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About This Item

线性分子式:
CH2[CH2NHC(CH2OH)3]2
CAS号:
分子量:
282.33
Beilstein:
1786109
EC號碼:
MDL號碼:
分類程式碼代碼:
12161700
PubChem物質ID:
NACRES:
NA.25

等級

BioPerformance Certified

品質等級

化驗

≥99.0%

形狀

crystals

技術

cell culture | mammalian: suitable

雜質

endotoxin and bioburden, tested

有用的pH值範圍

6.3-9.5

pKa (25 °C)

(1) 6.8, (2) 9.0

mp

164-165 °C (lit.)

應用

diagnostic assay manufacturing

異物活動

DNAse (exonuclease), NICKase (endonuclease), RNAse, and protease, none detected

SMILES 字串

OCC(CO)(CO)NCCCNC(CO)(CO)CO

InChI

1S/C11H26N2O6/c14-4-10(5-15,6-16)12-2-1-3-13-11(7-17,8-18)9-19/h12-19H,1-9H2

InChI 密鑰

HHKZCCWKTZRCCL-UHFFFAOYSA-N

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應用

  • Neutralized chimeric DNA probe for the improvement of GC-rich RNA detection specificity on the nanowire field-effect transistor.: BIS-TRIS propane is used in the development of nanowire field-effect transistors for detecting GC-rich RNA sequences. The study demonstrates the buffer′s role in enhancing the specificity and sensitivity of these biosensors (Chou et al., 2019).

  • Elimination of ghost peaks by optimization of anion exchange chromatography method for determination of gamma-carboxyglutamic acid (Gla)-domainless impurity in recombinant activated clotting factor VII drug products.: BIS-TRIS propane is employed in optimizing chromatography methods to eliminate ghost peaks during the analysis of pharmaceutical impurities. The buffer′s effectiveness ensures accurate and reliable detection of impurities in drug formulations (Tahmasbi et al., 2019).

其他說明

很容易将 BIS-TRIS 丙烷产品规格与 BIS-TRIS 丙烷规格表进行比较

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Joseph S Brunzelle et al.
Archives of biochemistry and biophysics, 474(1), 157-166 (2008-04-01)
The three-dimensional structure of the catalytically efficient beta-xylosidase from Selenomonas ruminantium in complex with competitive inhibitor 1,3-bis[tris(hydroxymethyl)methylamino]propane (BTP) was determined by using X-ray crystallography (1.3A resolution). Most H bonds between inhibitor and protein occur within subsite -1, including one between
Sami J O Varjo et al.
Journal of chromatography. A, 1081(1), 92-98 (2005-07-15)
Greater stability of liposome coatings and improved resolution of model steroids in capillary electrochromatography (CEC) were sought by adding small diamines (ethylenediamine, diaminopropane, bis-tris-propane, or N-(2-hydroxyethyl)piperazine-N'-(2-ethanesulfonic acid, HEPES)) to the liposome solution before coating of fused silica capillaries. The phospholipid
Sarita V Mello et al.
Biomacromolecules, 4(4), 968-973 (2003-07-15)
In this paper, we describe the preparation and characterization of Langmuir and Langmuir-Blodgett (LB) monolayers of the enzyme organophosphorus acid anhydrolase (OPAA). Langmuir films of OPAA were characterized on different subphases, such as phosphate, ammonium carbonate, and bis-tris-propane buffers. Monolayers
P Gómez-Tagle et al.
Inorganic chemistry, 40(15), 3786-3796 (2001-07-10)
Potentiometric titrations of the mixtures of lanthanide(III) perchlorates and bis-Tris propane (BTP) reveal formation of dinuclear hydroxo complexes M2(BTP)2(OH)n(6-n), where M = La(III), Pr(III), Nd(III), Eu(III), Gd(III), and Dy(III) and n = 2, 4, 5, or 6, in the pH
R Tóth-Boconádi et al.
Biophysical journal, 78(6), 3170-3177 (2000-05-29)
Buffers change the electric signals of light-excited bacteriorhodopsin molecules in purple membrane if their concentration and the pH of the low-salt solution are properly selected. "Positive" buffers produce a positive component, and "negative" buffers a negative component in addition to

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