B3412

小檗碱 半硫酸盐

≥95%

• 别名: 黄连素
• 线性分子式: C₂₀H₁₈NO₄ · 1/2SO₄
• CAS号: 633-66-9
• 分子量: 384.39
• 顏色索引編號: 75160
• MDL號碼: MFCD00031743
• 分類程式碼代碼: 12171500
• PubChem物質ID: 24891718
• NACRES: NA.32

属性

• 化驗: ≥95%
• 形狀: powder
• 溶解度: methanol: soluble
• SMILES 字串: [O-]S([O-])(=O)=O.COc1ccc2cc3-c4cc5OCOc5cc4CC[n+]3cc2c1OC.COc6ccc7cc8-c9cc%10OCOc%10cc9CC[n+]8cc7c6OC
• InChI: 1S/2C20H18NO4.H2O4S/c2*1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2;1-5(2,3)4/h2*3-4,7-10H,5-6,11H2,1-2H3;(H2,1,2,3,4)/q2*+1;/p-2
• InChI 密鑰: OJVABJMSSDUECT-UHFFFAOYSA-L

说明

應用

Fluorescent stain for heparin in mast cells

生化／生理作用

An alkaloid with weak antibiotic properties. Substrate for MDR efflux pumps. Antimicrobial activities of berberine is potentiated by the MDR inhibitor 5´-methoxyhydnocarpin (5´-MHC). Berberine upregulates the expression of Pgp in hepatoma cells. Treatment with berberine potentially results in the reduced accumulation of chemotherapeutic drugs.

安全信息

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H302
• 防範說明: P264 - P270 - P301 + P312 - P501
• 危險分類: Acute Tox. 4 Oral
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 個人防護裝備: dust mask type N95 (US), Eyeshields, Gloves