推荐产品
品質等級
化驗
≥98% (TLC)
形狀
powder
溶解度
H2O: ≤2 mg/mL (with sonication)
DMF: 50 mg/mL (Stable up to 2 months in dry DMF.)
儲存溫度
−20°C
SMILES 字串
[H][C@]12CS[C@@H](CCCCC(=O)NCCCCCC(=O)ON3C(=O)CCC3=O)[C@@]1([H])NC(=O)N2
InChI
1S/C20H30N4O6S/c25-15(7-4-3-6-14-19-13(12-31-14)22-20(29)23-19)21-11-5-1-2-8-18(28)30-24-16(26)9-10-17(24)27/h13-14,19H,1-12H2,(H,21,25)(H2,22,23,29)/t13-,14-,19-/m0/s1
InChI 密鑰
UVGHPGOONBRLCX-NJSLBKSFSA-N
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應用
生物素氨基己酸N-羟基琥珀酰亚胺酯已用于抗体的生物素化。
生化／生理作用
生物素是一种广泛应用于生物化学领域的标签，与亲和素高度亲和。当将生物素（小分子）偶联到生物聚合物（大分子）时，需要一个间隔链来减少空间位阻。生物素氨基己酸 N-羟基琥珀酰亚胺酯含有一个7原子间隔基和N-琥珀酰亚胺离去基。它能与pH值在6.5-8.5范围内的伯胺反应。这种生物素化试剂含有氨基丙基间隔体，因此可以减少亲和素与某些生物素化化合物结合时的空间位阻。
免責聲明
除非我们的产品目录或产品随附的其他公司文件中另有说明，否则我们的产品仅用于研究用途，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、体外或体内治疗用途或任何类型的人类或动物消费或应用。
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
其他客户在看
Alana M Thackray et al.
The Biochemical journal, 401(2), 475-483 (2006-10-05)
PrPSc [abnormal disease-specific conformation of PrP (prion-related protein)] accumulates in prion-affected individuals in the form of amorphous aggregates. Limited proteolysis of PrPSc results in a protease-resistant core of PrPSc of molecular mass of 27-30 kDa (PrP27-30). Aggregated forms of PrP
C Hughes et al.
Molecular therapy : the journal of the American Society of Gene Therapy, 3(4), 623-630 (2001-04-26)
Three strategies have been designed to concentrate infectious retroviral vectors from the supernatants of human- (HT1080) and murine- (NIH 3T3) based packaging cells. Streptavidin-conjugated paramagnetic particles in conjunction with (i) antibodies directed against murine fibronectin, (ii) biotinylated lectins, or (iii)
S M Costello et al.
Clinical chemistry, 25(9), 1572-1580 (1979-09-01)
Classically, one can increase the titer of an agglutinating or first antibody with an antiglobulin or second antibody. We have used an avidin-biotin system in place of antiglobulin to similarly extend the agglutination by an initial anticellular antibody. Erythrocytes were
Avidin binding of carboxyl-substituted biotin and analogues.
K Hofmann et al.
Biochemistry, 21(5), 978-984 (1982-03-02)
R Maya et al.
Genes & development, 15(9), 1067-1077 (2001-05-02)
The p53 tumor suppressor protein, a key regulator of cellular responses to genotoxic stress, is stabilized and activated after DNA damage. The rapid activation of p53 by ionizing radiation and radiomimetic agents is largely dependent on the ATM kinase. p53
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