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Merck

B1557

Sigma-Aldrich

透明质酸生物素 钠盐

≥97%, soluble powder

别名:

透明质酸生物素

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About This Item

MDL號碼:
分類程式碼代碼:
12352201
NACRES:
NA.25

應用

透明质酸生物素(HA-生物素)可用作特异性生物亲和探针,以检测组织和细胞中的HA结合蛋白(透明质酸粘素)、HA受体和HA结合成分。利用透明质酸生物素可开发用于固定化和纯化透明质酸粘素的亲和结合系统。 HA-生物素可用于水凝胶开发以及药物靶向。
一种高灵敏度探针,用于检测纳克级透明质酸结合蛋白(透明质酸粘素)。

其他說明

来自鸡冠或发酵。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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P Auvinen et al.
The American journal of pathology, 156(2), 529-536 (2000-02-10)
Hyaluronan (HA) is an extracellular matrix polysaccharide that promotes cell migration through its cell surface receptors and by effecting changes in the physical environment. HA expression is frequently increased in malignant tumors, whereas its association with the invasive potential and
T Pouyani et al.
Bioconjugate chemistry, 5(4), 370-372 (1994-07-01)
Hyaluronic acid (HA) is a linear polysaccharide composed of repeating disaccharide units of D-glucuronic acid (GlcUA) and N-acetyl-D-glucosamine (GlcNAc). Hyaluronate plays an important role in many biological processes as mediated by its interactions with a number of HA-binding proteins (the
D Liu et al.
Frontiers in bioscience : a journal and virtual library, 3, d631-d636 (1998-06-23)
CD44 is a cell surface glycoprotein present on many cell types. Many CD44 isoforms have been identified. All CD44 isoforms utilize identical transmembrane and cytoplasmic domains. The hematopoietic form of CD44 (CD44H) is the major CD44 protein present on normal
James Melrose et al.
Methods in molecular medicine, 101, 65-78 (2004-08-10)
Hyaluronan (HA) binding proteins (HABPs) were localized in cartilaginous ovine tissues (articular cartilage, intervertebral disc) using a biotinylated HA (bHA) oligosaccharide bioaffinity probe. The bHA oligosaccharide probe was prepared by partial digestion of HA with ovine testicular hyaluronidase, and the
Yuan Cui et al.
Applied biochemistry and biotechnology, 169(1), 239-249 (2012-11-28)
Hyaluronic acid is a naturally ionic polysaccharide with cancer cell selectivity. It is an ideal candidate material for delivery of anticancer agents. In this study, hyaluronic acid (HA) micro-hydrogel loaded with anticancer drugs was prepared by the biotin-avidin system approach.

商品

Glycosaminoglycans are large linear polysaccharides constructed of repeating disaccharide units.

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