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Key Documents

AV50878

Sigma-Aldrich

Anti-MDFIC (AB2) antibody produced in rabbit

affinity isolated antibody

别名:

Anti-HIC, Anti-MyoD family inhibitor domain containing

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About This Item

分類程式碼代碼:
12352203

生物源

rabbit

品質等級

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

分子量

37 kDa

物種活性

human

濃度

0.5 mg - 1 mg/mL

技術

western blot: suitable

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... MDFIC(29969)

免疫原

Synthetic peptide directed towards the middle region of human MDFIC

應用

Anti-MDFIC (AB2) antibody produced in rabbit is suitable for western blotting at a concentration of 1.0μg/ml.

生化/生理作用

MyoD family inhibitor domain containing (MDFIC) is involved in transcription regulation of viral genome expression. Alternate translation results in two isoforms, p40 and p32 found localized to cytoplasm and nucleolus, respectively.

序列

Synthetic peptide located within the following region: PQLQTSAQVPSGEEIGKIKNGHTGLSNGNGIHHGAKHGSADNRKLSAPVS

外觀

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Lili Gu et al.
Immunology letters, 123(2), 179-184 (2009-05-12)
The Human I-mfa domain-Containing protein, HIC, is a 246 amino acid protein that functions as a transcriptional regulator. Although the precise function of HIC remains to be clarified, the association of the HIC gene locus with myeloid neoplasms, its interactions
Ella Reiss-Sklan et al.
PloS one, 4(7), e6152-e6152 (2009-07-08)
Human I-mfa domain containing protein (HIC) differentially regulates transcription from viral promoters. HIC affects the Wnt pathway, the JNK/SAPK pathway and the activity of positive transcription elongation factor-b (P-TEFb). Studies exploring HIC function in mammalian cells used ectopically expressed HIC

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