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生物源
rabbit
品質等級
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
分子量
60 kDa
物種活性
human
濃度
0.5 mg - 1 mg/mL
技術
western blot: suitable
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... SLC22A11(55867)
免疫原
Synthetic peptide directed towards the C terminal region of human SLC22A11
應用
Anti-SLC22A11 (AB1) antibody produced in rabbit is suitable for western blotting at a concentration of 1.0μg/ml.
生化／生理作用
SLC22A11 (Organic Anion Transporter 4, OAT4) is a membrane protein involved in sodium-dependent transport and excretion of organic anions. This protein is expressed mainly in placenta and in the kidney. A variant of the gene encoding OAT4 has been implicated in the development of a major gout subtype called renal underexcretion type gout.
序列
Synthetic peptide located within the following region: ASSLVVLFFLPETQGLPLPDTIQDLESQKSTAAQGNRQEAVTVESTSL
外觀
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Masayuki Sakiyama et al.
Drug metabolism and pharmacokinetics, 29(2), 208-210 (2013-09-13)
Gout, a common disease, is a consequence of hyperuricemia, and increases the risks of hypertension, cardiovascular diseases, cerebrovascular diseases and renal failure. Gout can be classified into 3 types: the renal underexcretion (RUE) type, renal overload type and combined type.
James E Shima et al.
American journal of physiology. Renal physiology, 299(4), F767-F775 (2010-07-30)
Apical reabsorption from the urine has been shown to be important for such processes as the maintenance of critical metabolites in the blood and the excretion of nephrotoxic compounds. The solute carrier (SLC) transporter OAT4 (SLC22A11) is expressed on the
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