AV43340

Anti-RNF146 antibody produced in rabbit

IgG fraction of antiserum

• 别名: Anti-DKFZP434O1427, Anti-RP3-351K20.1, Anti-Ring finger protein 146, Anti-dJ351K20.1
• 分類程式碼代碼: 12352203
• NACRES: NA.41

属性

• 生物源: rabbit
• 品質等級: 100
• 共軛: unconjugated
• 抗體表格: IgG fraction of antiserum
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 形狀: buffered aqueous solution
• 分子量: 39 kDa
• 物種活性: mouse, horse, rat, human
• 濃度: 0.5 mg - 1 mg/mL
• 技術: western blot: suitable
• NCBI登錄號: NP_112225
• UniProt登錄號: Q9NTX7-2
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... RNF146(81847)

说明

一般說明

Ring finger protein 146 (RNF146, Iduna) is a poly(ADP-ribose) polymer binding and PARsylation dependent E3 ubiquitin ligase which ubiquitinates proteins for degradation by proteosomes. RNF146 is neuroprotective due to its inhibition of Parthanatos via binding with Poly(ADP-ribose) (PAR). RNF146 regulates Wnt signaling via ubiquitylation of auto-PARsylated tankyrase.

特異性

Anti-RNF146 polyclonal antibody reacts with human and mouse ring finger protein 146 proteins.

免疫原

Synthetic peptide directed towards the C terminal region of human RNF146

應用

Anti-RNF146 polyclonal antibody is used to tag ring finger protein 146 for detection and quantitation by Western blotting and in plasma by immunohistochemical (IHC) techniques. It is used as a probe to determine the roles ring finger protein 146 in Wnt signaling and neuroprotection.

序列

Synthetic peptide located within the following region: AVVAQHSLTQQRLLVSNANQTVPDRSDRSGTDRSVAGGGTVSVSVRSRRP

外觀

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全信息

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable