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Key Documents

AV34717

Sigma-Aldrich

抗TRIM31 兔抗

affinity isolated antibody

别名:

抗含三联基元31(Tripartite motif-containing 31)

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

品質等級

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

分子量

48 kDa

物種活性

human

濃度

0.5 mg - 1 mg/mL

技術

immunohistochemistry: suitable
western blot: suitable

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... TRIM31(11074)

一般說明

TRIM31是一种包含B-box、RING和卷曲螺旋三个锌结合结构域的蛋白质。TRIM31基因的改变与注意力缺陷/多动障碍(ADHD)有关,而蛋白质水平的变化与胃癌和非小细胞肺癌有关。
兔抗TRIM31抗体可识别人、牛和小鼠TRIM31。

免疫原

靶向人TRIM31 N末端区域的合成肽

應用

兔抗TRIM31抗体适用于蛋白印迹(0.5 μg/ml)和IHC(4-8 μg/ml)分析。

生化/生理作用

TRIM31编码三重基序(TRIM)家族的成员。TRIM基序包括三个锌结合结构域,RING、B-box1和B-box2以及卷曲螺旋结构域。该蛋白质定位于细胞质和细胞核。

序列

位于以下区域内的合成肽: CRESKDHKSHNVSLIEEAAQNYQGQIQEQIQVLQQKEKETVQVKAQGVHR

外觀

本品为溶于1x PBS缓冲液的纯化抗体,含 0.09% (w/v) 叠氮化钠和2%蔗糖。

免責聲明

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Hui Li et al.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 35(6), 5747-5752 (2014-02-26)
The present study aims to investigate expression pattern and biological roles of TRIM31 in human non-small cell lung cancer (NSCLC). We examined TRIM31 expression in 116 NSCLC tissues and 20 corresponding normal lung tissues by immumohistochemistry. We found TRIM31 downregulation
Thais S Rizzi et al.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 156(2), 145-157 (2011-02-09)
Intelligence is a highly heritable trait for which it has proven difficult to identify the actual genes. In the past decade, five whole-genome linkage scans have suggested genomic regions important to human intelligence; however, so far none of the responsible
Shenglan Zeng et al.
Redox biology, 45, 102058-102058 (2021-07-05)
Tripartite motif (TRIM) 31 has been implicated in diverse biological and pathological conditions. However, whether TRIM31 plays a role in ischemic stroke progression is not clarified. Here we demonstrated that TRIM31 was significantly downregulated in the ischemic brain and the
Takeyuki Sugiura
Cell biology international, 35(7), 657-661 (2011-01-15)
TRIM (tripartite motif) family proteins, comprising RING finger, B-box and coiled-coil domains, are involved in various cellular processes including tumour development and antiviral response. One of the family proteins, TRIM31, was originally identified as a gene induced by growth-suppressive retinoid.
Shigao Yang et al.
Science advances, 5(5), eaav7999-eaav7999 (2019-06-01)
The mitochondrial antiviral signaling protein (MAVS) orchestrates host antiviral innate immune response to RNA virus infection. However, how MAVS signaling is controlled to eradicate virus while preventing self-destructive inflammation remains obscure. Here, we show that protein geranylgeranylation, a posttranslational lipid

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