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品質等級
化驗
≥99% (TLC)
形狀
powder
顏色
off-white to faint yellow
mp
177-180 °C
儲存溫度
2-8°C
InChI
1S/C6H6N2O3/c1-4-2-7-3-5(6(9)10)8(4)11/h2-3H,1H3,(H,9,10)
InChI 密鑰
DNRXJHATQULEHC-UHFFFAOYSA-N
生化／生理作用
阿昔莫司又称氧甲吡嗪，是一种烟酸类似物。它可用作抗脂解药和血管扩张剂。阿西莫司可用于胰岛素和生长素释放肽相关的各种代谢研究。它可降低总胆固醇和总甘油三酯，从而有助于治疗高脂血症。
已经研究了烟酸衍生的血管舒张剂的降脂作用。
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
Feipeng Jin et al.
Biochemical and biophysical research communications, 428(1), 86-92 (2012-10-13)
Saturated fatty acids (FA) have been linked to an increased risk of cardiovascular disease. The effects of acipimox, a FA-lowering agent, on palmitate- (an important saturated fatty acid) stimulated atherosclerosis remains to be elucidated. We investigated the effects of acipimox
Inflammation and lipid accumulation in xanthoma disseminatum: Therapeutic considerations.
Klaus Eisendle et al.
Journal of the American Academy of Dermatology, 58(2 Suppl), S47-S49 (2008-01-23)
Effect of the antilipolytic nicotinic acid analogue acipimox on whole-body and skeletal muscle glucose metabolism in patients with non-insulin-dependent diabetes mellitus.
Vaag A, et al.
The Journal of Clinical Investigation, 88(4), 1282-1290 (1991)
Lars C Gormsen et al.
European journal of endocrinology, 154(5), 667-673 (2006-04-29)
Concentrations of the orexigenic peptide ghrelin is affected by a number of hormones, which also affect circulating levels of free fatty acids (FFAs). The present study was therefore designed to determine the direct effect of FFAs on circulating ghrelin. Eight
Jara Nedvidkova et al.
Regulatory peptides, 167(1), 134-139 (2011-01-18)
Ghrelin is predominantly produced by the stomach and the growth hormone (GH)-ghrelin feedback loop between the stomach and the pituitary gland has recently been suggested. The disruption of the gut-brain axis might be involved in bulimia nervosa (BN). We investigated
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