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Key Documents

A7223

Sigma-Aldrich

白蛋白 人

recombinant, expressed in Pichia pastoris, 5% in aqueous buffer, ≥90% (SDS-PAGE)

别名:

Albagen, rHSA

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About This Item

经验公式(希尔记法):
C2936H4624N786O889S41
CAS号:
分子量:
66471.53
MDL號碼:
分類程式碼代碼:
12352202
NACRES:
NA.25

生物源

human

品質等級

重組細胞

expressed in Pichia pastoris

化驗

≥90% (SDS-PAGE)

形狀

solution

分子量

monomer ~67 kDa

濃度

5% in aqueous buffer

技術

cell culture | mammalian: suitable

UniProt登錄號

運輸包裝

wet ice

儲存溫度

2-8°C

InChI

1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11

InChI 密鑰

QYSGYZVSCZSLHT-UHFFFAOYSA-N

基因資訊

human ... ALB(213)

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應用

该重组变异建议用于:吸收、分散、代谢和排泄(ADME)药理学研究;细胞培养;药物递送研究;细胞冻存。

生化/生理作用

白蛋白是可见于动物体液和组织及部分植物种子的一类可溶性单体蛋白。 血清白蛋白可作为类固醇、脂肪酸和甲状腺激素的载体蛋白。 血清白蛋白在调节血液的胶体渗透压方面也至关重要。

物理性質

Asp N末端缺失的重组构建体。X射线晶体学证实了其与天然白蛋白的结构等同性。Asp N末端是主要的Cu2+和Ni2+ 螯合位点;其缺失消除了一个重要的抗原决定簇,让蛋白质具有低过敏源性。还可在Cys34处阻断,改善稳定性、单体含量和均质性。

外觀

磷酸盐缓冲盐水溶液,含有4 mM辛酸钠和 4 mM N-乙酰色氨酸。

其他說明

更多信息参见人血清白蛋白

法律資訊

Albagen is a trademark of Albumin Therapeutics, LLC.

儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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