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生物源
rabbit
品質等級
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
lyophilized powder
物種活性
human, mouse, rat
技術
flow cytometry: suitable (indirect)
immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable
UniProt登錄號
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... AQP4(361)
mouse ... Aqp4(11829)
rat ... Aqp4(25293)
一般說明
AQP4是一种调节中枢神经系统水流量的渗透压感受器。它在星形胶质细胞中含量丰富，而在肺、肠、眼和肾组织中含量较少。兔抗水通道蛋白4抗体可识别人、小鼠和大鼠中的水通道蛋白4。
免疫原
对应于与GST融合的大鼠AQP4的残基249-323的重组融合蛋白。
應用
兔抗水通道蛋白4抗体可用于免疫组化。该抗体还可用于免疫细胞化学、蛋白质印迹和流式细胞术应用。
生化／生理作用
使用2μl/mll的兔抗AQP4作为一抗，对使用GFP-AQP4转染的HEK-293细胞进行免疫沉淀和蛋白质印迹分析。
外觀
从含有1%牛血清白蛋白和0.05%叠氮化钠的磷酸盐缓冲盐水（pH 7.4）中冻干。
免責聲明
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Gry Fluge Vindedal et al.
Molecular and cellular neurosciences, 77, 47-52 (2016-11-05)
There is a constitutive production of water in brain. The efflux routes of this excess water remain to be identified. We used basal brain water content as a proxy for the capacity of water exit routes. Basal brain water content
Paraneoplastic Neuromyelitis Optica Associated with Lung Adenocarcinoma in a Young Woman.
Kyoung Won Baik et al.
Journal of clinical neurology (Seoul, Korea), 14(2), 246-247 (2018-04-10)
Ian F Kimbrough et al.
Brain : a journal of neurology, 138(Pt 12), 3716-3733 (2015-11-26)
Reduced cerebral blood flow impairs cognitive function and ultimately causes irreparable damage to brain tissue. The gliovascular unit, composed of neural and vascular cells, assures sufficient blood supply to active brain regions. Astrocytes, vascular smooth muscle cells, and pericytes are
Michelle Figueroa et al.
JAMA neurology, 71(4), 495-498 (2014-04-16)
Reports of neuromyelitis optica spectrum disorder (NMOSD) occurring in the setting of neoplasia suggest that aquaporin-4 autoimmunity may in some cases have a paraneoplastic basis. In this case report, we describe a patient with NMOSD whose test results were seropositive
Krysti L Todd et al.
Frontiers in aging neuroscience, 9, 445-445 (2018-01-31)
Ventriculomegaly (expansion of the brain's fluid-filled ventricles), a condition commonly found in the aging brain, results in areas of gliosis where the ependymal cells are replaced with dense astrocytic patches. Loss of ependymal cells would compromise trans-ependymal bulk flow mechanisms
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